4-nitrobenzyl trans-3-(2-tert-butyldimethylsilyloxycyclopentyl)propiolate

Base Information

Chemical Name:4-nitrobenzyl trans-3-(2-tert-butyldimethylsilyloxycyclopentyl)propiolate
CAS No.:83651-56-3
Molecular Formula:C₂₁H₂₉NO₅Si
Molecular Weight:403.55
Hs Code.:

Synonyms:4-nitrobenzyl trans-3-(2-tert-butyldimethylsilyloxycyclopentyl)propiolate

Suppliers and Price of 4-nitrobenzyl trans-3-(2-tert-butyldimethylsilyloxycyclopentyl)propiolate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-nitrobenzyl trans-3-(2-tert-butyldimethylsilyloxycyclopentyl)propiolate

Chemical Property:

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Technology Process of 4-nitrobenzyl trans-3-(2-tert-butyldimethylsilyloxycyclopentyl)propiolate

There total 2 articles about 4-nitrobenzyl trans-3-(2-tert-butyldimethylsilyloxycyclopentyl)propiolate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: trans-3-(2-tert-butyldimethylsilyloxycyclopentyl)ethyne lithium

: 4457-32-3
4-nitrobenzyl chloroformate

: 83651-56-3
4-nitrobenzyl trans-3-(2-tert-butyldimethylsilyloxycyclopentyl)propiolate

Guidance literature:: In tetrahydrofuran; at -50 - -40 ℃; for 0.666667h;
DOI:10.1248/cpb.34.1434

Reference yield:

: 67902-26-5,75557-69-6
tert-Butyl-((1R,2S)-2-ethynyl-cyclopentyloxy)-dimethyl-silane

: 4457-32-3
4-nitrobenzyl chloroformate

: 83651-56-3
4-nitrobenzyl trans-3-(2-tert-butyldimethylsilyloxycyclopentyl)propiolate

Guidance literature:: 2.) -78 degC, THF;
DOI:10.1016/S0040-4039(00)88437-3

Reference yield:

: 83651-56-3
[2-(tert-Butyl-dimethyl-silanyloxy)-cyclopentyl]-propynoic acid 4-nitro-benzyl ester

: 83651-58-5
4-nitrobenzyl 3-(1-cyclopentenyl)-3-oxopropanoate

Guidance literature:: Multi-step reaction with 2 steps

1: benzene / 48 h / Heating

2: oxalic acid*2H₂O / diethyl ether; ethanol / Ambient temperature

With oxalic acid; In diethyl ether; ethanol; benzene;
DOI:10.1248/cpb.34.1434