trans-5-fluoro-2,2-dimethyl-6-(phenylseleno)-1,3-dioxepane

Base Information

• Chemical Name: trans-5-fluoro-2,2-dimethyl-6-(phenylseleno)-1,3-dioxepane
• CAS No.: 128913-70-2
• Molecular Formula: C₁₃H₁₇FO₂Se
• Molecular Weight: 303.235
• Mol file: 128913-70-2.mol

Synonyms:trans-5-fluoro-2,2-dimethyl-6-(phenylseleno)-1,3-dioxepane

Chemical Property of trans-5-fluoro-2,2-dimethyl-6-(phenylseleno)-1,3-dioxepane

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of trans-5-fluoro-2,2-dimethyl-6-(phenylseleno)-1,3-dioxepane

There total 2 articles about trans-5-fluoro-2,2-dimethyl-6-(phenylseleno)-1,3-dioxepane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

2,2-dimethyl-4,7-dihydro-1,3-dioxepin (1003-83-4) + N-phenylselanylphthalimide (71098-88-9) → trans-5-fluoro-2,2-dimethyl-6-(phenylseleno)-1,3-dioxepane (128913-70-2)

Guidance literature:

With triethylamine tris(hydrogen fluoride); In dichloromethane; at 25 ℃; for 7h;

DOI:10.1016/S0040-4039(00)94596-9

Reference yield: 17.0%

2,2-dimethyl-4,7-dihydro-1,3-dioxepin (1003-83-4) + N-phenylselanylphthalimide (71098-88-9) → trans-5-fluoro-2,2-dimethyl-6-(phenylseleno)-1,3-dioxepane (128913-70-2) + (+/-)-(5S,6S)-2,2-dimethyl-6-(phenylseleno)-1,3-dioxepan-5-ol

Guidance literature:

With triethylamine tris(hydrogen fluoride); In dichloromethane; at 25 ℃; for 7h;

upstream raw materials:

2,2-dimethyl-4,7-dihydro-1,3-dioxepin

N-phenylselanylphthalimide