N-(PHENYLSELENO)PHTHALIMIDE

Base Information

• Chemical Name: N-(PHENYLSELENO)PHTHALIMIDE
• CAS No.: 71098-88-9
• Molecular Formula: C14H9NO2Se
• Molecular Weight: 302.191
• Hs Code.: 2925190090
• Mol file: 71098-88-9.mol

Synonyms:N-(PHENYLSELENO)PHTHALIMIDE;NPSP;N-(PHENYLSELENO)PHTHALIMIDE, TECH.;N-(Phenylseleno)phthalimide,94%

Chemical Property of N-(PHENYLSELENO)PHTHALIMIDE

Chemical Property:

• Appearance/Colour: white to light yellow crystalline powder
• Vapor Pressure: 3.96E-08mmHg at 25°C
• Melting Point: 181-184 °C
• Boiling Point: 445.4°C at 760 mmHg
• PKA: -2.90±0.20(Predicted)
• Flash Point: 223.2°C
• PSA: 37.38000
• LogP: 1.16520
• Storage Temp.: Freezer (-20°C)
• Sensitive.: Air Sensitive

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-(Phenylseleno)phthalimide technical grade ^*data from reagent suppliers

Safty Information:

• Pictogram(s): N-T,N,T
• Hazard Codes: N-T,N,T
• Statements: 50/53-33-23/25
• Safety Statements: 61-60-45-28A-20/21-28

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: N-(Phenylseleno)phthalimide is a versatile selenamide reagent and has been used:to selectively derivatize thiols for mass spectrometric analysisto derivatize thiol peptides in protein digestsin L-prolinamide or pyrrolidine trifluoromethanesulfonamide promoted α-selenenylation reactions of aldehydes and ketonesfor introducing PhSe into protected glycals, ketones, aldehydes, stannanes and exocyclic alkenes

Technology Process of N-(PHENYLSELENO)PHTHALIMIDE

There total 5 articles about N-(PHENYLSELENO)PHTHALIMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

Phenylselenyl chloride (5707-04-0) + potassium phtalimide (1074-82-4) → N-phenylselanylphthalimide (71098-88-9)

Guidance literature:

In hexane; at 25 ℃; for 2h;

DOI:10.1016/S0040-4020(01)96722-5

Reference yield:

Phenylselenyl bromide (34837-55-3) + potassium phtalimide (1074-82-4) → N-phenylselanylphthalimide (71098-88-9)

Guidance literature:

In Petroleum ether; at 20 ℃; for 2h; Time; Inert atmosphere;

Reference yield:

phthalimide (136918-14-4,85-41-6) → N-phenylselanylphthalimide (71098-88-9)

Guidance literature:

Multi-step reaction with 2 steps

1: NaOCl / diethyl ether; H₂O / 1 h / 0 °C

2: diethyl ether / 2 h / Ambient temperature

With sodium hypochlorite; In diethyl ether; water;

DOI:10.1016/S0040-4039(00)94651-3

upstream raw materials:

Phenylselenyl chloride

potassium phtalimide

N-chlorophthalimide

sodium phenylselenide

Downstream raw materials:

1-phenyl-2-(phenylselanyl)ethanol

Se-phenyl(selenothioperoxy)benzoate

butyl phenyl selenide

trans-7-fluoro-6-(phenylseleno)-1,4-dioxaspiro<4,5>decane