benzyl 2-bromo-4-chlorobutanoate

Base Information

Chemical Name:benzyl 2-bromo-4-chlorobutanoate
CAS No.:304909-62-4
Molecular Formula:C₁₁H₁₂BrClO₂
Molecular Weight:291.572
Hs Code.:

Synonyms:benzyl 2-bromo-4-chlorobutanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of benzyl 2-bromo-4-chlorobutanoate

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Technology Process of benzyl 2-bromo-4-chlorobutanoate

There total 2 articles about benzyl 2-bromo-4-chlorobutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 71254-32-5
2-bromo-4-chloro-butyric acid chloride

: 100-51-6,185532-71-2
benzyl alcohol

: 304909-62-4
benzyl 2-bromo-4-chlorobutanoate

Guidance literature:: In tetrahydrofuran; at 0 ℃; for 15h; Inert atmosphere;
DOI:10.1021/ja5109084

Reference yield:

: 304909-62-4
benzyl 2-bromo-4-chlorobutanoate

Guidance literature:

Reference yield: 80.0%

: 304909-62-4
benzyl 2-bromo-4-chlorobutanoate

: 100-58-3
phenylmagnesium bromide

: (R)-benzyl 4-chloro-2-phenylbutanoate

: (S)-benzyl 4-chloro-2-phenylbutanoate

Guidance literature:: With (4S,4S')-(-)-2,2'-(1-methylethylidene)bis[4,5-dihydro-4-(phenylmethyl)oxazole]; cobalt(II) iodide; In tetrahydrofuran; diethyl ether; at -80 ℃; for 6h; Schlenk technique; Inert atmosphere;
DOI:10.1021/ja5109084