11-benzylcarbamoylundecanoic acid 2-(11-benzylcarbamoylundecanoyloxy)-3-dimethylaminopropyl ester

Base Information

• Chemical Name: 11-benzylcarbamoylundecanoic acid 2-(11-benzylcarbamoylundecanoyloxy)-3-dimethylaminopropyl ester
• CAS No.: 794501-07-8
• Molecular Formula: C₄₃H₆₇N₃O₆
• Molecular Weight: 722.021
• Mol file: 794501-07-8.mol

Synonyms:11-benzylcarbamoylundecanoic acid 2-(11-benzylcarbamoylundecanoyloxy)-3-dimethylaminopropyl ester

Chemical Property of 11-benzylcarbamoylundecanoic acid 2-(11-benzylcarbamoylundecanoyloxy)-3-dimethylaminopropyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 11-benzylcarbamoylundecanoic acid 2-(11-benzylcarbamoylundecanoyloxy)-3-dimethylaminopropyl ester

There total 6 articles about 11-benzylcarbamoylundecanoic acid 2-(11-benzylcarbamoylundecanoyloxy)-3-dimethylaminopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

3-(dimethylamino)-1,2-propanediol (623-57-4) + 11-benzylcarbamoylundecanoic acid (783305-26-0) → 11-benzylcarbamoylundecanoic acid 2-(11-benzylcarbamoylundecanoyloxy)-3-dimethylaminopropyl ester (794501-07-8)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 48h;

DOI:10.1021/ja0474906

Reference yield:

1,12-dodecanedioic acid (693-23-2) → 11-benzylcarbamoylundecanoic acid 2-(11-benzylcarbamoylundecanoyloxy)-3-dimethylaminopropyl ester (794501-07-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 50 percent / DCC / tetrahydrofuran / 24 h

2: 46 percent / DMAP; DCC / CH₂Cl₂ / 48 h

With dmap; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ja0474906

Reference yield:

benzylamine (100-46-9) → 11-benzylcarbamoylundecanoic acid 2-(11-benzylcarbamoylundecanoyloxy)-3-dimethylaminopropyl ester (794501-07-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 50 percent / DCC / tetrahydrofuran / 24 h

2: 46 percent / DMAP; DCC / CH₂Cl₂ / 48 h

With dmap; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ja0474906

upstream raw materials:

3-(dimethylamino)-1,2-propanediol

11-benzylcarbamoylundecanoic acid

1,12-dodecanedioic acid

benzylamine