5-Azaspiro[2.4]heptan-4-one

Base Information

Chemical Name:5-Azaspiro[2.4]heptan-4-one
CAS No.:3697-70-9
Molecular Formula:C₆H₉NO
Molecular Weight:111.144
Hs Code.:
European Community (EC) Number:894-368-7
Mol file:3697-70-9.mol

Synonyms:5-azaspiro[2.4]heptan-4-one;3697-70-9;6-Azaspiro[2.4]heptan-7-one;MFCD19219354;SCHEMBL479513;5-?Azaspiro[2.4]?heptan-?4-?one;AKOS006354325;PB47826;BS-43065;SY045014;CS-0133442;EN300-743353

Suppliers and Price of 5-Azaspiro[2.4]heptan-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
5-Azaspiro[2.4]heptan-4-one
1g
$ 540.00

Matrix Scientific
5-Azaspiro[2.4]heptan-4-one
10g
$ 1764.00

Matrix Scientific
5-Azaspiro[2.4]heptan-4-one
5g
$ 1260.00

Crysdot
5-Azaspiro[2.4]heptan-4-one 95+%
1g
$ 918.00

Chemenu
5-Azaspiro[2.4]heptan-4-one 95%
1g
$ 866.00

American Custom Chemicals Corporation
5-AZASPIRO[2.4]HEPTAN-4-ONE 95.00%
5MG
$ 452.22

Total 8 raw suppliers

Chemical Property of 5-Azaspiro[2.4]heptan-4-one

Chemical Property:

Boiling Point:302.6±11.0 °C(Predicted)
PKA:16.37±0.20(Predicted)
Density:1.16±0.1 g/cm3(Predicted)
XLogP3:0
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:111.068413911
Heavy Atom Count:8
Complexity:138

Purity/Quality:

99%, ^*data from raw suppliers

5-Azaspiro[2.4]heptan-4-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC12CCNC2=O

Technology Process of 5-Azaspiro[2.4]heptan-4-one

There total 7 articles about 5-Azaspiro[2.4]heptan-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 3697-69-6
ethyl 1-(cyanomethyl)cyclopropanecarboxylate

: 3697-70-9
4-oxo-5-azaspiro<2.4>heptane

Guidance literature:: With ammonia; hydrogen; In methanol; at 20 - 27 ℃; for 48h;

Reference yield: 34.0%

: 126822-35-3
ethyl N-carbethoxy-1-(2-aminoethyl)cyclopropanecarboxylate

: 3697-70-9
4-oxo-5-azaspiro<2.4>heptane

Guidance literature:: With barium dihydroxide; In methanol; for 14h; Heating;
DOI:10.1021/jo00297a025

Reference yield:

: 126822-34-2
ethyl 1-(2-carboxyethyl)cyclopropanecarboxylate

: 3697-70-9
4-oxo-5-azaspiro<2.4>heptane

Guidance literature:: Multi-step reaction with 2 steps

1: 1) triethylamine, diphenyl phosphorazidate / 1) toluene, 75 deg C, 4 h; 2) reflux, 12 h

2: 34 percent / Ba(OH)2*8H₂O / methanol / 14 h / Heating

With barium dihydroxide; diphenyl phosphoryl azide; triethylamine; In methanol;
DOI:10.1021/jo00297a025