Ethyl 1-(hydroxymethyl)cyclopropanecarboxylate

Base Information

• Chemical Name: Ethyl 1-(hydroxymethyl)cyclopropanecarboxylate
• CAS No.: 3697-68-5
• Molecular Formula: C7H12O3
• Molecular Weight: 144.17
• Hs Code.: 2918199090
• European Community (EC) Number: 844-793-9
• DSSTox Substance ID: DTXSID50498796
• Nikkaji Number: J1.138.823J
• Wikidata: Q82349084
• Mol file: 3697-68-5.mol

Synonyms:3697-68-5;ethyl 1-(hydroxymethyl)cyclopropanecarboxylate;1-Hydroxymethyl-cyclopropanecarboxylic acid ethyl ester;Ethyl 1-(hydroxymethyl)cyclopropane-1-carboxylate;MFCD09759206;Ethyl 1-hydroxymethylcyclopropanecarboxylate;Ethyl 1-hydroxymethyl-cyclopropanecarboxylate;SCHEMBL164041;DTXSID50498796;PAILVKQSHRJIPE-UHFFFAOYSA-N;Cyclopropanecarboxylic acid, 1-(hydroxymethyl)-, ethyl ester;BCP14500;AKOS006326934;CS-W018860;AM803789;DS-15134;SY045896;ethyl1-(hydroxymethyl)cyclopropanecarboxylate;FT-0696306;EN300-85010;ethyl 1-hydroxymethyl-1-cyclopropanecarboxylate;A874228;1-(Hydroxymethyl)cyclopropanecarboxylic acid ethyl ester;1-hydroxymethyl-cyclopropane carboxylic acid ethyl ester

Chemical Property of Ethyl 1-(hydroxymethyl)cyclopropanecarboxylate

Chemical Property:

• Boiling Point: 90-94 °C(Press: 8 Torr)
• PKA: 15.10±0.10(Predicted)
• PSA: 46.53000
• Density: 1.159±0.06 g/cm3(Predicted)
• LogP: 0.32200
• Storage Temp.: 2-8°C
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 144.078644241
• Heavy Atom Count: 10
• Complexity: 138

Purity/Quality:

97% ^*data from raw suppliers

Ethyl1-(Hydroxymethyl)cyclopropanecarboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C1(CC1)CO
• Uses: Ethyl 1-(hydroxymethyl)cyclopropanecarboxylate acts as a ligand for Suzuki coupling reaction.

Technology Process of Ethyl 1-(hydroxymethyl)cyclopropanecarboxylate

There total 5 articles about Ethyl 1-(hydroxymethyl)cyclopropanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

diethyl cyclopropane-1,1-dicarboxylate (1559-02-0) → ethyl 1-(hydroxymethyl)cyclopropanecarboxylate (3697-68-5)

Guidance literature:

With lithium tri(t-butoxy)aluminum hydride; In tetrahydrofuran; at 23 - 65 ℃; for 24h;

Reference yield: 61.0%

1,1-cyclopropanedicarboxylic acid monoethyl ester (3697-66-3) → ethyl 1-(hydroxymethyl)cyclopropanecarboxylate (3697-68-5)

Guidance literature:

1,1-cyclopropanedicarboxylic acid monoethyl ester; With triethylamine; isobutyl chloroformate; In tetrahydrofuran; at -10 - 0 ℃; for 1h;

With sodium tetrahydroborate; water; In tetrahydrofuran; at 0 ℃; for 1h;

Reference yield:

1,1-cyclopropanedicarboxylic acid monoethyl ester (3697-66-3) + isopropyl chloroformate (108-23-6) → ethyl 1-(hydroxymethyl)cyclopropanecarboxylate (3697-68-5)

Guidance literature:

1,1-cyclopropanedicarboxylic acid monoethyl ester; isopropyl chloroformate; With triethylamine; In tetrahydrofuran; at -10 - 0 ℃; for 1h;

With sodium tetrahydroborate; In tetrahydrofuran; water; at 0 ℃; for 1h;

upstream raw materials:

diethyl cyclopropane-1,1-dicarboxylate

1,1-cyclopropanedicarboxylic acid monoethyl ester

diethyl malonate

isopropyl chloroformate

Downstream raw materials:

C₂₁H₃₅N₃O₅

C₂₃H₂₀N₂O₅S

C₂₁H₁₆N₂O₅S

1-(difluoromethyl)cyclopropane-1-carboxylic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 3697-68-5 1-HYDROXYMETHYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER

Send

Send

Metric Ton KG G Pound L ML

Send

Send