Tr-PEG5

Base Information

• Chemical Name: Tr-PEG5
• CAS No.: 125274-16-0
• Molecular Formula: C27H32O5
• Molecular Weight: 436.548
• DSSTox Substance ID: DTXSID20468360
• Nikkaji Number: J1.237.147K
• Wikidata: Q82295534
• Mol file: 125274-16-0.mol

Synonyms:Tr-PEG5;125274-16-0;Tr-PEG4-OH;1,1,1-TRIPHENYL-2,5,8,11-TETRAOXATRIDECAN-13-OL;2-[2-[2-(2-trityloxyethoxy)ethoxy]ethoxy]ethanol;2,5,8,11-Tetraoxatridecan-13-ol, 1,1,1-triphenyl-;3,6,9,12-Tetraoxatridecan-1-ol, 13,13,13-triphenyl-;SCHEMBL2821674;YSZC1128;DTXSID20468360;NVNUQXMSFVIKJG-UHFFFAOYSA-N;MFCD22574816;AKOS037646431;AS-68779;BP-20702;HY-126883;CS-0107981;W16655;11-Triphenylmethyloxy-3,6,9-trioxaundecan-1-ol

Chemical Property of Tr-PEG5

Chemical Property:

• PSA: 57.15000
• LogP: 4.03720
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 15
• Exact Mass: 436.22497412
• Heavy Atom Count: 32
• Complexity: 407

Purity/Quality:

98% ^*data from raw suppliers

Tr-Peg5 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OCCOCCOCCOCCO
• Description: Tr-PEG5 is a PEG linker containing a trityl, alcohol protecting group and a terminal hydroxyl group. Trityl can be removed under acidic conditions. The hydroxyl group can undergo various reactions in order to further derivatize the compound. The hydrophilic PEG linkers increase the solubility of compounds in aqueous media.

Technology Process of Tr-PEG5

There total 7 articles about Tr-PEG5 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Tetraethylene glycol (112-60-7) + trityl chloride (76-83-5) → 1,1,1-triphenyl-2,5,8,11-tetraoxatridecan-13-ol (125274-16-0)

Guidance literature:

With pyridine; at 45 ℃;

DOI:10.1016/j.tetlet.2010.04.078

Reference yield: 55.0%

2-<2-(triphenylmethoxy)ethoxy>ethyl methanesulfonate (146462-58-0) + diethylene glycol (111-46-6) → 1,1,1-triphenyl-2,5,8,11-tetraoxatridecan-13-ol (125274-16-0)

Guidance literature:

diethylene glycol; With potassium tert-butylate; In tert-butyl alcohol; for 0.5h; Reflux;

2-<2-(triphenylmethoxy)ethoxy>ethyl methanesulfonate; In tert-butyl alcohol; for 13h; Reflux;

DOI:10.1021/acs.jmedchem.8b00041

Reference yield: 31.0%

Tetraethylene glycol (112-60-7) + trityl chloride (76-83-5) → triphenylmethyl alcohol (76-84-6) + 1,1,1-triphenyl-2,5,8,11-tetraoxatridecan-13-ol (125274-16-0)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; water; benzene; for 24h; Heating;

upstream raw materials:

triphenylmethyl alcohol

Tetraethylene glycol

trityl chloride

2-<2-(triphenylmethoxy)ethoxy>ethyl methanesulfonate

Downstream raw materials:

1,1,1,33,33,33-hexaphenyl-2,5,8,11,14,17,20,23,26,29,32-dodecaaoxatritriacontane

α-(2-azidoethyl)-ω-hydroxyhexa(oxyethylene)

23-amino-3 ,6,9,12,15,18,21-heptaoxatricosan-1-ol

29-amino-3,6,9,12,15,18,21,24,27-nonaoxanonacosan-1-ol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 125274-16-0 2,5,8,11-Tetraoxatridecan-13-ol, 1,1,1-triphenyl-

Send

Send

Metric Ton KG G Pound L ML

Send

Send