(4R,5S)-3-((2S,3S)-1-oxo-2,3-dimethyl-5-(trimethylsilyl)-4-pentynyl)-4-methyl-5-phenyl-2-oxazolidinone-dicobalt hexacarbonyl

Base Information

• Chemical Name: (4R,5S)-3-((2S,3S)-1-oxo-2,3-dimethyl-5-(trimethylsilyl)-4-pentynyl)-4-methyl-5-phenyl-2-oxazolidinone-dicobalt hexacarbonyl
• CAS No.: 109530-31-6
• Molecular Formula: C₂₆H₂₇Co₂NO₉Si
• Molecular Weight: 643.574
• Mol file: 109530-31-6.mol

Synonyms:(4R,5S)-3-((2S,3S)-1-oxo-2,3-dimethyl-5-(trimethylsilyl)-4-pentynyl)-4-methyl-5-phenyl-2-oxazolidinone-dicobalt hexacarbonyl

Chemical Property of (4R,5S)-3-((2S,3S)-1-oxo-2,3-dimethyl-5-(trimethylsilyl)-4-pentynyl)-4-methyl-5-phenyl-2-oxazolidinone-dicobalt hexacarbonyl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (4R,5S)-3-((2S,3S)-1-oxo-2,3-dimethyl-5-(trimethylsilyl)-4-pentynyl)-4-methyl-5-phenyl-2-oxazolidinone-dicobalt hexacarbonyl

There total 1 articles about (4R,5S)-3-((2S,3S)-1-oxo-2,3-dimethyl-5-(trimethylsilyl)-4-pentynyl)-4-methyl-5-phenyl-2-oxazolidinone-dicobalt hexacarbonyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

Co2(CO)6((CH3)3SiCCCHCH3OCH3) (102286-03-3) + (4R,5S)-4-methyl-5-phenyl-3-propionyloxazolidin-2-one (77877-20-4) → (4R,5S)-3-((2S,3S)-1-oxo-2,3-dimethyl-5-(trimethylsilyl)-4-pentynyl)-4-methyl-5-phenyl-2-oxazolidinone-dicobalt hexacarbonyl (109530-31-6) + (4R,5S)-3-((2S,3R)-1-oxo-2,3-dimethyl-5-(trimethylsilyl)-4-pentynyl)-4-methyl-5-phenyl-2-oxazolidinone-dicobalt hexacarbonyl (109583-44-0)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; Ar; soln. of propionimide, triflate cooled to 0 ° C, addn. of amine, soln. stirred for 15 min,boron enolate cooled to -78 ° C,Co compd. was added under Ar;soln. warmed to 0 .degree Cmixt. partitioned between pH 7 phosphate buffer,CH2Cl2;; extn. with CH2Cl2;evapn.,diastereomer ratios (12:1) determined by HPLC and (1)H NMR;flash chromy. (ethyl acetate/hexane),elem. anal. for major product;;

DOI:10.1021/ja00253a030

upstream raw materials:

Co₂(CO)6((CH₃)3SiCCCHCH₃OCH₃)

(4R,5S)-4-methyl-5-phenyl-3-propionyloxazolidin-2-one