(2-chloroethoxy)-(3,4,5-trifluorophenyl)acetic acid N'-{(E)-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]acryloyl}hydrazide

Base Information

Chemical Name:(2-chloroethoxy)-(3,4,5-trifluorophenyl)acetic acid N'-{(E)-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]acryloyl}hydrazide
CAS No.:949167-28-6
Molecular Formula:C₂₄H₂₂ClF₃N₄O₄
Molecular Weight:522.911
Hs Code.:

Synonyms:(2-chloroethoxy)-(3,4,5-trifluorophenyl)acetic acid N'-{(E)-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]acryloyl}hydrazide

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Chemical Property of (2-chloroethoxy)-(3,4,5-trifluorophenyl)acetic acid N'-{(E)-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]acryloyl}hydrazide

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Technology Process of (2-chloroethoxy)-(3,4,5-trifluorophenyl)acetic acid N'-{(E)-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]acryloyl}hydrazide

There total 1 articles about (2-chloroethoxy)-(3,4,5-trifluorophenyl)acetic acid N'-{(E)-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]acryloyl}hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 870839-41-1
(E)-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]acrylic acid

: 949167-27-5
tert-butyl N'-[2-(2-chloroethoxy)-2-(3,4,5-trifluorophenyl)acetyl]hydrazinecarboxylate

: 949167-28-6
(2-chloroethoxy)-(3,4,5-trifluorophenyl)acetic acid N'-{(E)-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]acryloyl}hydrazide

Guidance literature:: tert-butyl N'-[2-(2-chloroethoxy)-2-(3,4,5-trifluorophenyl)acetyl]hydrazinecarboxylate; With hydrogenchloride; water; In ethyl acetate; at 20 ℃; for 1h;

(E)-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]acrylic acid; With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 2h;

Reference yield:

: 949167-28-6
(2-chloroethoxy)-(3,4,5-trifluorophenyl)acetic acid N'-{(E)-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]acryloyl}hydrazide

: (-)-2-{(E)-2-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]vinyl}-8-(3,4,5-trifluorophenyl)-5,6-dihydro-8H-[1,2,4]triazolo[5,1-c][1,4]oxazine

Guidance literature:: (2-chloroethoxy)-(3,4,5-trifluorophenyl)acetic acid N'-{(E)-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]acryloyl}hydrazide; With trichlorophosphate; at 120 ℃; for 5h;

With ammonium acetate; acetic acid; at 150 ℃; for 15h;