Tert-butyl N-(8-bromooctyl)carbamate

Base Information

Chemical Name:Tert-butyl N-(8-bromooctyl)carbamate
CAS No.:142356-35-2
Molecular Formula:C₁₃H₂₆BrNO₂
Molecular Weight:308.259
Hs Code.:
European Community (EC) Number:889-214-0
DSSTox Substance ID:DTXSID601263522

Synonyms:142356-35-2;Tert-butyl N-(8-bromooctyl)carbamate;tert-Butyl (8-bromooctyl)carbamate;N-Boc-8-bromooctan-1-amine;Tert-butylN-(8-bromooctyl)carbamate;N-BOC-8-amino-1-bromooctane;SCHEMBL7292779;N-BOC-8-BROMOOCTYLAMINE;tert-Butyl(8-bromooctyl)carbamate;XBDSVMQPKSQVMH-UHFFFAOYSA-N;DTXSID601263522;AMY16363;MFCD24473139;BS-44786;1,1-Dimethylethyl N-(8-bromooctyl)carbamate;CS-0043308;A1-00725

Suppliers and Price of Tert-butyl N-(8-bromooctyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Tert-butyl N-(8-bromooctyl)carbamate

Chemical Property:

XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:10
Exact Mass:307.11469
Heavy Atom Count:17
Complexity:202

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCCCCCCCCBr

Technology Process of Tert-butyl N-(8-bromooctyl)carbamate

There total 5 articles about Tert-butyl N-(8-bromooctyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 144183-31-3
N-(8-hydroxyoctyl)carbamic acid tert-butyl ester

: 142356-35-2
8-amino>octyl bromide

Guidance literature:: With bromine; triethylamine; triphenylphosphine; In dichloromethane; at 0 - 20 ℃; for 12h;
DOI:10.1002/anie.201602355

Reference yield:

: 30100-16-4
8-tert-butoxycarbonylaminooctanoic acid

: 142356-35-2
8-amino>octyl bromide

Guidance literature:: Multi-step reaction with 2 steps

1: BH₃ / tetrahydrofuran / 1 h

2: Ph₃P, CBr₄ / tetrahydrofuran; acetonitrile / 24 h

With carbon tetrabromide; borane; triphenylphosphine; In tetrahydrofuran; acetonitrile;
DOI:10.1021/jm00042a007

Reference yield:

: 19008-71-0
8-aminooctan-1-ol

: 142356-35-2
8-amino>octyl bromide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / water; acetonitrile / 20 °C / Inert atmosphere

2: triphenylphosphine; carbon tetrabromide; potassium carbonate / dichloromethane / 20 °C / Inert atmosphere

With carbon tetrabromide; potassium carbonate; triphenylphosphine; sodium hydroxide; In dichloromethane; water; acetonitrile;
DOI:10.1021/acschembio.8b00790