Linarin

Base Information

Chemical Name:Linarin
CAS No.:480-36-4
Molecular Formula:C28H32O14
Molecular Weight:592.554
Hs Code.:29389090
European Community (EC) Number:207-547-6
UNII:HBH2I685IU
DSSTox Substance ID:DTXSID40197382
Nikkaji Number:J6.164F
Wikidata:Q1775837
Metabolomics Workbench ID:140770
ChEMBL ID:CHEMBL509502
Mol file:480-36-4.mol

Synonyms:acaciin;linarin

Suppliers and Price of Linarin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Linarine
5mg
$ 496.00

Usbiological
Linarin
5mg
$ 368.00

Usbiological
Linarin
20mg
$ 326.00

TRC
Linarine
25mg
$ 225.00

Medical Isotopes, Inc.
Linarine
10 mg
$ 775.00

Medical Isotopes, Inc.
Linarine
5 mg
$ 675.00

JR MediChem
Buddleoside 98%
20mg
$ 600.00

DC Chemicals
Linarin >98%,StandardReferencesGrade
20 mg
$ 280.00

Crysdot
Linarin 95+%
10mg
$ 90.00

ChemScene
Linarin ≥98.0%
20mg
$ 180.00

Total 95 raw suppliers

Chemical Property of Linarin

Chemical Property:

Appearance/Colour:white to off white powder
Melting Point:258-260 °C
Boiling Point:885.2 °C at 760 mmHg
PKA:6.11±0.40(Predicted)
Flash Point:292.2 °C
PSA：217.97000
Density:1.62 g/cm³
LogP:-0.79530
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:Acetic Acid (Very Slightly, Heated), Acetonitrile (Slightly), DMSO (Slightly), M
XLogP3:-0.5
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:14
Rotatable Bond Count:7
Exact Mass:592.17920569
Heavy Atom Count:42
Complexity:955

Purity/Quality:

95%-98% ^*data from raw suppliers

Linarine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC=C(C=C5)OC)O)O)O)O)O)O)O
Isomeric SMILES:C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC=C(C=C5)OC)O)O)O)O)O)O)O
Uses Linarine (Diosmin EP Impurity E) is a naturally occurring flavone glycoside that was identified to possess potential sedative and anticonvulsant properties.

Technology Process of Linarin

There total 4 articles about Linarin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 771480-96-7
3'-O-(1-phenyltetrazol-5-yl)diosmin

: 480-36-4
acacetin 7-O-rutinoside

Guidance literature:: With ammonium formate; palladium on activated charcoal; In methanol; for 5h; Heating;
DOI:10.1021/np040079b

Reference yield:

: 520-27-4
diosmin

: 480-36-4
acacetin 7-O-rutinoside

Guidance literature:: Multi-step reaction with 2 steps

1: 40 percent / KHCO₃ / dimethylformamide / 2 h / 80 °C

2: 53 percent / HCOONH₄ / Pd/C / methanol / 5 h / Heating

With ammonium formate; potassium hydrogencarbonate; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/np040079b

Reference yield:

: 480-44-4
5,7-dihydroxy-2-(4'-methoxyphenyl)-4H-1-benzopyran-4-one

: 4154-21-6
O²,O³,O⁴-triacetyl-O⁶-(tri-O-acetyl-α-L-rhamnopyranosyl)-α-D-glucopyranosyl bromide

: 480-36-4
acacetin 7-O-rutinoside

Guidance literature:: With potassium hydroxide; acetone; Erhitzen des Reaktionsprodukts mit Acetanhydrid und Pyridin und Erwaermen des isolierten Reaktionsprodukts mit wss.-aethanol. Natronlauge;