Technology Process of C35H33F3N2O7
There total 6 articles about C35H33F3N2O7 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
C20H21F6N3O2; potassium carbonate;
In
dichloromethane;
at 20 ℃;
for 24h;
optical yield given as %ee;
enantioselective reaction;
DOI:10.1002/chem.201200478
- Guidance literature:
-
Multi-step reaction with 2 steps
1: N-Bromosuccinimide; triphenylphosphine / dichloromethane / 3 h / Cooling with ice
2: C20H21F6N3O2; potassium carbonate / dichloromethane / 24 h / 20 °C
With
N-Bromosuccinimide; C20H21F6N3O2; potassium carbonate; triphenylphosphine;
In
dichloromethane;
DOI:10.1002/chem.201200478
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: thionyl chloride / 0 - 20 °C
2.1: sodium hydride / tetrahydrofuran / 2 h / 0 °C
2.2: 4 h
3.1: hydrogenchloride / water; dimethyl sulfoxide / 3 h / 20 °C
4.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 °C
5.1: N-Bromosuccinimide; triphenylphosphine / dichloromethane / 3 h / Cooling with ice
6.1: C20H21F6N3O2; potassium carbonate / dichloromethane / 24 h / 20 °C
With
hydrogenchloride; N-Bromosuccinimide; lithium aluminium tetrahydride; thionyl chloride; C20H21F6N3O2; sodium hydride; potassium carbonate; triphenylphosphine;
In
tetrahydrofuran; dichloromethane; water; dimethyl sulfoxide;
DOI:10.1002/chem.201200478
