α-methylbenzyldimethyl(trimethylsilylmethyl)ammonium iodide

Base Information

• Chemical Name: α-methylbenzyldimethyl(trimethylsilylmethyl)ammonium iodide
• CAS No.: 133302-71-3
• Molecular Formula: C₁₄H₂₆NSi*I
• Molecular Weight: 363.357
• Mol file: 133302-71-3.mol

Synonyms:α-methylbenzyldimethyl(trimethylsilylmethyl)ammonium iodide

Chemical Property of α-methylbenzyldimethyl(trimethylsilylmethyl)ammonium iodide

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-methylbenzyldimethyl(trimethylsilylmethyl)ammonium iodide

There total 1 articles about α-methylbenzyldimethyl(trimethylsilylmethyl)ammonium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

N-methyl-N-(trimethylsilylmethyl)-α-methylbenzylamine (133302-66-6) + methyl iodide (74-88-4) → α-methylbenzyldimethyl(trimethylsilylmethyl)ammonium iodide (133302-71-3)

Guidance literature:

In acetonitrile; at 60 ℃; for 1h;

DOI:10.1055/s-1991-26393

Reference yield: 29.0%

α-methylbenzyldimethyl(trimethylsilylmethyl)ammonium iodide (133302-71-3) → styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + N,N-dimethyl-2-phenylpropan-1-amine hydrochloride salt (7560-81-8,88466-32-4) + (Z)-5-ethylidene-6-(dimethylamino)methyl-1,3-cyclohexadiene (133302-80-4) + (E)-5-ethylidene-6-(dimethylamino)methyl-1,3-cyclohexadiene (133751-05-0)

Guidance literature:

With cesium fluoride; In N,N-dimethyl-formamide; at 10 ℃; for 0.5h; Product distribution;

DOI:10.1055/s-1991-26393

Reference yield:

α-methylbenzyldimethyl(trimethylsilylmethyl)ammonium iodide (133302-71-3) → styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + N,N-dimethyl-2-phenylpropan-1-amine hydrochloride salt (7560-81-8,88466-32-4) + 2-(dimethylaminomethylphenyl)ethylbenzene (52728-16-2)

Guidance literature:

With potassium hydroxide; cesium fluoride; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) DMF, 10 deg C, 0,5 h, 2.) EtOH, 60 deg C, 24 h;

DOI:10.1055/s-1991-26393

upstream raw materials:

N-methyl-N-(trimethylsilylmethyl)-α-methylbenzylamine

methyl iodide

Downstream raw materials:

styrene

N,N-dimethyl-2-phenylpropan-1-amine hydrochloride salt

2-(dimethylaminomethylphenyl)ethylbenzene

(Z)-5-ethylidene-6-(dimethylamino)methyl-1,3-cyclohexadiene