Technology Process of (3-amino-2,4-dimethoxyphenyl)(3,4,5-trimethoxyphenyl)methanone
There total 5 articles about (3-amino-2,4-dimethoxyphenyl)(3,4,5-trimethoxyphenyl)methanone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
N-[2,6-dimethoxy-3-(3,4,5-trimethoxybenzoyl)phenyl]acetamide;
With
hydrogenchloride; water;
In
methanol;
at 80 ℃;
for 24h;
With
ammonia; water;
In
methanol;
pH=7;
DOI:10.1016/j.bmc.2011.08.047
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: dichloromethane / 24 h / 20 °C / Inert atmosphere
2.1: methanesulfonic acid; phosphorus pentoxide / 24 h / 60 °C / Inert atmosphere
3.1: hydrogenchloride; water / methanol / 24 h / 80 °C
3.2: pH 7
With
hydrogenchloride; methanesulfonic acid; phosphorus pentoxide; water;
In
methanol; dichloromethane;
2.1: Friedel Crafts acylation;
DOI:10.1016/j.bmc.2011.08.047
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium carbonate / acetone / 1 h / Inert atmosphere; Reflux
2.1: hydrogenchloride; tin(II) chloride dihdyrate / diethyl ether / 30 h / 20 °C
3.1: dichloromethane / 24 h / 20 °C / Inert atmosphere
4.1: methanesulfonic acid; phosphorus pentoxide / 24 h / 60 °C / Inert atmosphere
5.1: hydrogenchloride; water / methanol / 24 h / 80 °C
5.2: pH 7
With
hydrogenchloride; methanesulfonic acid; tin(II) chloride dihdyrate; phosphorus pentoxide; water; potassium carbonate;
In
methanol; diethyl ether; dichloromethane; acetone;
4.1: Friedel Crafts acylation;
DOI:10.1016/j.bmc.2011.08.047
![N-[2,6-dimethoxy-3-(3,4,5-trimethoxybenzoyl)phenyl]acetamide](/Databaselist/images/loading.webp)
