2734-70-5 Usage
Description
2,6-DIMETHOXYANILINE is an organic compound with the chemical formula C8H11NO2. It is an off-white solid and is known for its potential applications in various industries due to its unique chemical properties.
Uses
Used in Chemical Research:
2,6-DIMETHOXYANILINE is used as a research compound for studying the degradation process of 2,6-dimethylaniline through the Fenton process. This helps in understanding the reactions involved in the oxidation of 2,6-dimethylaniline under various reaction conditions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,6-DIMETHOXYANILINE is used as a starting material for the synthesis of various drugs, such as local anesthetics like lidocaine. It is used as a precursor for the production of these drugs due to its reactivity and compatibility with other chemical compounds.
Used in Analytical Chemistry:
2,6-DIMETHOXYANILINE is used as a reference compound in the development of gas chromatographic-mass spectrometric assays. It helps in the detection of hemoglobin adducts covalently bound to rat hemoglobin after administration of either 2,6-dimethylaniline or lidocaine, which is crucial for understanding the metabolic pathways and potential toxic effects of these compounds.
Used in Environmental Applications:
2,6-DIMETHOXYANILINE can be used in environmental applications for the study of pollutant degradation and removal processes. Its reactivity and chemical properties make it a suitable candidate for investigating the effectiveness of various treatment methods in reducing the environmental impact of pollutants.
Check Digit Verification of cas no
The CAS Registry Mumber 2734-70-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,7,3 and 4 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2734-70:
(6*2)+(5*7)+(4*3)+(3*4)+(2*7)+(1*0)=85
85 % 10 = 5
So 2734-70-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H11NO2/c1-10-6-4-3-5-7(11-2)8(6)9/h3-5H,9H2,1-2H3
2734-70-5Relevant articles and documents
Nickel(ii)-catalyzed asymmetric thio-Claisen rearrangement of α-diazo pyrazoleamides with thioindoles
Yang, Wei,Lin, Xiaobin,Zhang, Yongyan,Cao, Weidi,Liu, Xiaohua,Feng, Xiaoming
, p. 10002 - 10005 (2020/09/15)
A nickel(ii) catalyzed enantioselective thio-Claisen rearrangement of α-diazo pyrazoleamides with thioindoles was realized with modified chiral N,N′-dioxide ligands, affording a variety of C3-substituted indole derivatives in high yields (up to 95%) with excellent enantioselectivities (up to 96% ee) under mild reaction conditions. A possible transition state model was proposed based on previous reports and the X-ray crystal structure of the catalyst.
Deacetylative Amination of Acetyl Arenes and Alkanes with C-C Bond Cleavage
Hyodo, Kengo,Hasegawa, Genna,Maki, Hiroya,Uchida, Kingo
supporting information, p. 2818 - 2822 (2019/04/25)
The Br?nsted acid-catalyzed synthesis of primary amines from acetyl arenes and alkanes with C-C bond cleavage is described. Although the conversion from an acetyl group to amine has traditionally required multiple steps, the method described herein, which uses an oxime reagent as an amino group source, achieves the transformation directly via domino transoximation/Beckmann rearrangement/Pinner reaction. The method was also applied to the synthesis of γ-aminobutyric acids, such as baclophen and rolipram.
Kolbe-Schmitt type reaction under ambient conditions mediated by an organic base
Sadamitsu, Yuta,Okumura, Akira,Saito, Kodai,Yamada, Tohru
supporting information, p. 9837 - 9840 (2019/08/20)
The combined use of an organic base for resorcinols realized a Kolbe-Schmitt type reaction under ambient conditions. When resorcinols (3-hydroxyphenol derivatives) were treated with DBU under a carbon dioxide atmosphere, nucleophilic addition to carbon dioxide proceeded to afford the corresponding salicylic acid derivatives in high yields.