(S)-2-(dibenzylamino)-3-(3,5-difluorophenyl)-N-methoxy-N-methylpropanamide

Base Information

Chemical Name:(S)-2-(dibenzylamino)-3-(3,5-difluorophenyl)-N-methoxy-N-methylpropanamide
CAS No.:1221264-42-1
Molecular Formula:C₂₅H₂₆F₂N₂O₂
Molecular Weight:424.49
Hs Code.:

Synonyms:(S)-2-(dibenzylamino)-3-(3,5-difluorophenyl)-N-methoxy-N-methylpropanamide

Suppliers and Price of (S)-2-(dibenzylamino)-3-(3,5-difluorophenyl)-N-methoxy-N-methylpropanamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-2-(dibenzylamino)-3-(3,5-difluorophenyl)-N-methoxy-N-methylpropanamide

Chemical Property:

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Technology Process of (S)-2-(dibenzylamino)-3-(3,5-difluorophenyl)-N-methoxy-N-methylpropanamide

There total 2 articles about (S)-2-(dibenzylamino)-3-(3,5-difluorophenyl)-N-methoxy-N-methylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

: 1221264-41-0
(S)-2-amino-3-(3,5-difluorophenyl)-N-methoxy-N-methylpropanamide

: 100-39-0
benzyl bromide

: 1221264-42-1
(S)-2-(dibenzylamino)-3-(3,5-difluorophenyl)-N-methoxy-N-methylpropanamide

Guidance literature:: With potassium carbonate; In ethanol; water; at 20 ℃; for 18h;

Reference yield:

: 362480-01-1
(S)-tert-butyl 3-(3,5-difluorophenyl)-1-(methoxy(methyl)amino)-1-oxopropan-2-ylcarbamate

: 1221264-42-1
(S)-2-(dibenzylamino)-3-(3,5-difluorophenyl)-N-methoxy-N-methylpropanamide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / 1,4-dioxane / 4 h / 0 - 20 °C

2: potassium carbonate / ethanol; water / 18 h / 20 °C

With hydrogenchloride; potassium carbonate; In 1,4-dioxane; ethanol; water;

Reference yield: 99.0%

: 1221264-42-1
(S)-2-(dibenzylamino)-3-(3,5-difluorophenyl)-N-methoxy-N-methylpropanamide

: 845543-61-5
(S)-N,N-dibenzyl-3,5-difluorophenyl-alaninal

Guidance literature:: (S)-2-(dibenzylamino)-3-(3,5-difluorophenyl)-N-methoxy-N-methylpropanamide; With lithium aluminium tetrahydride; In diethyl ether; at 0 ℃; for 1h;

With sodium hydrogen sulfate; water; In diethyl ether;