Technology Process of (2R,3S,4S)-4-(benzyloxy)-1-<(tert-butyldimethylsilyl)oxy>-2,5-dimethyl-3-hexanol
There total 8 articles about (2R,3S,4S)-4-(benzyloxy)-1-<(tert-butyldimethylsilyl)oxy>-2,5-dimethyl-3-hexanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 87 percent / H2SO4
2: 80 percent / TfOH
3: 89 percent / LAH
4: 70 percent / SO3*pyridine, DMSO, Et3N
5: 74 percent / SnCl4 / CH2Cl2 / -78 °C
6: LAH
7: 100 percent / DMAP, Et3N
With
dmap; lithium aluminium tetrahydride; pyridine-SO3 complex; trifluorormethanesulfonic acid; tin(IV) chloride; dimethyl sulfoxide; triethylamine;
sulfuric acid;
In
dichloromethane;
DOI:10.1016/S0040-4039(01)80647-X
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 57 percent / 1N H2SO4, 1N NaNO2
2: 87 percent / H2SO4
3: 80 percent / TfOH
4: 89 percent / LAH
5: 70 percent / SO3*pyridine, DMSO, Et3N
6: 74 percent / SnCl4 / CH2Cl2 / -78 °C
7: LAH
8: 100 percent / DMAP, Et3N
With
dmap; lithium aluminium tetrahydride; pyridine-SO3 complex; trifluorormethanesulfonic acid; sulfuric acid; tin(IV) chloride; dimethyl sulfoxide; triethylamine; sodium nitrite;
sulfuric acid;
In
dichloromethane;
DOI:10.1016/S0040-4039(01)80647-X