N-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-phthalimide

Base Information

Chemical Name:N-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-phthalimide
CAS No.:118489-92-2
Molecular Formula:C₂₄H₁₉N₃O₃
Molecular Weight:397.433
Hs Code.:

<i>N</i>-[2-(4-oxo-2-phenyl-3,4-dihydro-2<i>H</i>-quinazolin-1-yl)-ethyl]-phthalimide

Synonyms:N-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-phthalimide

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Chemical Property of N-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-phthalimide

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Technology Process of N-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-phthalimide

There total 4 articles about N-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-phthalimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 100-52-7
benzaldehyde

: 55409-95-5
2-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethylamino]-benzamide

: 118489-92-2
N-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-phthalimide

Guidance literature:: piperidine; In xylene; for 5h; Heating;
DOI:10.1002/ardp.19883211116

Reference yield:

: 574-98-1
2-(2-bromoethyl)isoindoline-1,3-dione

: 118489-92-2
N-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-phthalimide

Guidance literature:: Multi-step reaction with 2 steps

1: 45 percent / dimethylformamide / 24 h / 65 - 70 °C

2: 66 percent / piperidine / xylene / 5 h / Heating

piperidine; In N,N-dimethyl-formamide; xylene;
DOI:10.1002/ardp.19883211116

Reference yield:

: 28144-70-9,88-68-6
anthranilic acid amide

: 118489-92-2
N-[2-(4-oxo-2-phenyl-3,4-dihydro-2H-quinazolin-1-yl)-ethyl]-phthalimide

Guidance literature:: Multi-step reaction with 2 steps

1: 45 percent / dimethylformamide / 24 h / 65 - 70 °C

2: 66 percent / piperidine / xylene / 5 h / Heating

piperidine; In N,N-dimethyl-formamide; xylene;
DOI:10.1002/ardp.19883211116