2-[(5-fluoro-2-{[6-(4-methyl-1-piperazinyl)-3-pyridinyl]amino}-4-pyrimidinyl)amino]-N-(1-methylethyl)benzamide hydrochloride

Base Information

• Chemical Name: 2-[(5-fluoro-2-{[6-(4-methyl-1-piperazinyl)-3-pyridinyl]amino}-4-pyrimidinyl)amino]-N-(1-methylethyl)benzamide hydrochloride
• CAS No.: 1089653-50-8
• Molecular Formula: C₂₄H₂₉FN₈O*ClH
• Molecular Weight: 501.007
• Mol file: 1089653-50-8.mol

Synonyms:2-[(5-fluoro-2-{[6-(4-methyl-1-piperazinyl)-3-pyridinyl]amino}-4-pyrimidinyl)amino]-N-(1-methylethyl)benzamide hydrochloride

Chemical Property of 2-[(5-fluoro-2-{[6-(4-methyl-1-piperazinyl)-3-pyridinyl]amino}-4-pyrimidinyl)amino]-N-(1-methylethyl)benzamide hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[(5-fluoro-2-{[6-(4-methyl-1-piperazinyl)-3-pyridinyl]amino}-4-pyrimidinyl)amino]-N-(1-methylethyl)benzamide hydrochloride

There total 1 articles about 2-[(5-fluoro-2-{[6-(4-methyl-1-piperazinyl)-3-pyridinyl]amino}-4-pyrimidinyl)amino]-N-(1-methylethyl)benzamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

2-[(2-chloro-5-fluoro-4-pyrimidinyl)amino]-N-(1-methylethyl)benzamide (1089653-96-2) + 6-(4-methyl-1-piperazinyl)-3-pyridinamine hydrochloride (1234971-67-5,82205-57-0) → 2-[(5-fluoro-2-{[6-(4-methyl-1-piperazinyl)-3-pyridinyl]amino}-4-pyrimidinyl)amino]-N-(1-methylethyl)benzamide hydrochloride (1089653-50-8)

Guidance literature:

2-[(2-chloro-5-fluoro-4-pyrimidinyl)amino]-N-(1-methylethyl)benzamide; 6-(4-methyl-1-piperazinyl)-3-pyridinamine hydrochloride; In isopropyl alcohol; at 100 ℃; for 120h;

With sodium hydroxide; water; pH=13;

With hydrogenchloride; In chloroform; water;

upstream raw materials:

2-[(2-chloro-5-fluoro-4-pyrimidinyl)amino]-N-(1-methylethyl)benzamide

6-(4-methyl-1-piperazinyl)-3-pyridinamine hydrochloride