(2R,4S,5R)-1,1-dibromo-4-(4'-methoxybenzyloxy)-3,5-dimethylhept-1,6-diene

Base Information

Chemical Name:(2R,4S,5R)-1,1-dibromo-4-(4'-methoxybenzyloxy)-3,5-dimethylhept-1,6-diene
CAS No.:521078-46-6
Molecular Formula:C₁₇H₂₂Br₂O₂
Molecular Weight:418.168
Hs Code.:

Synonyms:(2R,4S,5R)-1,1-dibromo-4-(4'-methoxybenzyloxy)-3,5-dimethylhept-1,6-diene

Suppliers and Price of (2R,4S,5R)-1,1-dibromo-4-(4'-methoxybenzyloxy)-3,5-dimethylhept-1,6-diene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,4S,5R)-1,1-dibromo-4-(4'-methoxybenzyloxy)-3,5-dimethylhept-1,6-diene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,4S,5R)-1,1-dibromo-4-(4'-methoxybenzyloxy)-3,5-dimethylhept-1,6-diene

There total 4 articles about (2R,4S,5R)-1,1-dibromo-4-(4'-methoxybenzyloxy)-3,5-dimethylhept-1,6-diene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 558-13-4
carbon tetrabromide

: 521078-86-4
(2R,3S,4R)-3-(4'-methoxybenzyloxy)-2,4-dimethylhex-5-enal

: 521078-46-6
(2R,4S,5R)-1,1-dibromo-4-(4'-methoxybenzyloxy)-3,5-dimethylhept-1,6-diene

Guidance literature:: With triphenylphosphine; In dichloromethane; at 0 ℃; for 1h;
DOI:10.1021/ol034248f

Reference yield:

: 2186-92-7
p-Anisaldehyde dimethyl acetal

: 521078-46-6
(2R,4S,5R)-1,1-dibromo-4-(4'-methoxybenzyloxy)-3,5-dimethylhept-1,6-diene

Guidance literature:: Multi-step reaction with 4 steps

1: 91 percent / p-TsOH / CHCl₃ / 1.42 h / 20 °C

2: 87 percent / DIBAL-H / CH₂Cl₂ / 2 h / -10 °C

3: 94 percent / Dess-Martin periodinane / CH₂Cl₂ / 2 h / 20 °C

4: 87 percent / PPh₃ / CH₂Cl₂ / 1 h / 0 °C

With diisobutylaluminium hydride; Dess-Martin periodane; toluene-4-sulfonic acid; triphenylphosphine; In dichloromethane; chloroform; 3: Dess-Martin oxidation;
DOI:10.1021/ol034248f

Reference yield:

: 521078-88-6
(4S,5R)-2-(4-Methoxy-phenyl)-5-methyl-4-((R)-1-methyl-allyl)-[1,3]dioxane

: 521078-46-6
(2R,4S,5R)-1,1-dibromo-4-(4'-methoxybenzyloxy)-3,5-dimethylhept-1,6-diene

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / DIBAL-H / CH₂Cl₂ / 2 h / -10 °C

2: 94 percent / Dess-Martin periodinane / CH₂Cl₂ / 2 h / 20 °C

3: 87 percent / PPh₃ / CH₂Cl₂ / 1 h / 0 °C

With diisobutylaluminium hydride; Dess-Martin periodane; triphenylphosphine; In dichloromethane; 2: Dess-Martin oxidation;
DOI:10.1021/ol034248f