C₃₅H₄₇NO₃Si

Base Information

• Chemical Name: C₃₅H₄₇NO₃Si
• CAS No.: 943912-65-0
• Molecular Formula: C₃₅H₄₇NO₃Si
• Molecular Weight: 557.849
• Mol file: 943912-65-0.mol

Synonyms:C₃₅H₄₇NO₃Si

Chemical Property of C₃₅H₄₇NO₃Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₃₅H₄₇NO₃Si

There total 3 articles about C₃₅H₄₇NO₃Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C18H23NO3 (943912-64-9) + (2-(4-bromophenyl)ethynyl)triisopropylsilane (271242-20-7) → C35H47NO3Si (943912-65-0)

Guidance literature:

With sodium t-butanolate; 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In toluene; at 90 ℃; for 24h;

DOI:10.1021/ja071057p

Reference yield:

2-(4-bromophenoxy)ethanol (34743-88-9) → C35H47NO3Si (943912-65-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / sodium tert-butoxide / 1,1-bis(diphenylphosphino)ferrocene; tris(dibenzylideneacetone)dipalladium / toluene / 24 h / 90 °C

2: sodium tert-butoxide / 1,1-bis(diphenylphosphino)ferrocene; tris(dibenzylideneacetone)dipalladium / toluene / 24 h / 90 °C

With sodium t-butanolate; 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In toluene; 1: Buchwald-Hartwig reaction / 2: Buchwald-Hartwig reaction;

DOI:10.1021/ja071057p

Reference yield:

tris-iso-propylsilyl acetylene (89343-06-6) → C35H47NO3Si (943912-65-0)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / PdCl₂(PPh₃)2; CuI / tetrahydrofuran / Heating

2: sodium tert-butoxide / 1,1-bis(diphenylphosphino)ferrocene; tris(dibenzylideneacetone)dipalladium / toluene / 24 h / 90 °C

With triethylamine; sodium t-butanolate; bis-triphenylphosphine-palladium(II) chloride; 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; copper(l) iodide; In tetrahydrofuran; toluene; 1: Sonogashira coupling / 2: Buchwald-Hartwig reaction;

DOI:10.1021/ja071057p

upstream raw materials:

C₁₈H₂₃NO₃

(2-(4-bromophenyl)ethynyl)triisopropylsilane

2-(4-bromophenoxy)ethanol

tris-iso-propylsilyl acetylene

Downstream raw materials:

C₂₆H₂₇NO₃

C₇₉H₈₈N₂O₇