(β-R)-ethyl 2-bromo-β-[[(S)-(1,1-dimethylethyl)sulfinyl]amino]-4-fluorobenzenepropanoate

Base Information

Chemical Name:(β-R)-ethyl 2-bromo-β-[[(S)-(1,1-dimethylethyl)sulfinyl]amino]-4-fluorobenzenepropanoate
CAS No.:934346-17-5
Molecular Formula:C₁₅H₂₁BrFNO₃S
Molecular Weight:394.305
Hs Code.:

Synonyms:(β-R)-ethyl 2-bromo-β-[[(S)-(1,1-dimethylethyl)sulfinyl]amino]-4-fluorobenzenepropanoate

Suppliers and Price of (β-R)-ethyl 2-bromo-β-[[(S)-(1,1-dimethylethyl)sulfinyl]amino]-4-fluorobenzenepropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (β-R)-ethyl 2-bromo-β-[[(S)-(1,1-dimethylethyl)sulfinyl]amino]-4-fluorobenzenepropanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (β-R)-ethyl 2-bromo-β-[[(S)-(1,1-dimethylethyl)sulfinyl]amino]-4-fluorobenzenepropanoate

There total 2 articles about (β-R)-ethyl 2-bromo-β-[[(S)-(1,1-dimethylethyl)sulfinyl]amino]-4-fluorobenzenepropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1039750-61-2
(S,E)-N-(2-bromo-4-fluorobenzylidene)-2-methylpropane-2-sulfinamide

: 105-36-2
ethyl bromoacetate

: 934346-17-5
(β-R)-ethyl 2-bromo-β-[[(S)-(1,1-dimethylethyl)sulfinyl]amino]-4-fluorobenzenepropanoate

Guidance literature:: ethyl bromoacetate; With copper(l) chloride; zinc; In tetrahydrofuran; at 50 - 90 ℃; for 1.33333h;

(S,E)-N-(2-bromo-4-fluorobenzylidene)-2-methylpropane-2-sulfinamide; In tetrahydrofuran; at 0 ℃; for 4h;

Reference yield:

: 59142-68-6
2-bromo-4-fluorobenzaldehyde

: 934346-17-5
(β-R)-ethyl 2-bromo-β-[[(S)-(1,1-dimethylethyl)sulfinyl]amino]-4-fluorobenzenepropanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: titanium(IV) tetraethanolate / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere

2.1: zinc; copper(l) chloride / tetrahydrofuran / 0.83 h / 50 °C

2.2: 4 h / 0 °C

With titanium(IV) tetraethanolate; copper(l) chloride; zinc; In tetrahydrofuran; 2.1: |Reformatsky Reaction / 2.2: |Reformatsky Reaction;
DOI:10.1021/jm501107q