(S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-4-phenylbutanoic acid

Base Information

• Chemical Name: (S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-4-phenylbutanoic acid
• CAS No.: 658691-36-2
• Molecular Formula: C₂₀H₂₈N₂O₄
• Molecular Weight: 360.453

Synonyms:(S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-4-phenylbutanoic acid

Chemical Property of (S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-4-phenylbutanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-4-phenylbutanoic acid

There total 2 articles about (S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-4-phenylbutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(S)-ethyl 2-((S)-3-acetamido-3-((R)-sec-butyl)-2-oxopyrrolidin-1-yl)-4-phenylbutanoate → (S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-4-phenylbutanoic acid (658691-36-2)

Guidance literature:

(S)-ethyl 2-((S)-3-acetamido-3-((R)-sec-butyl)-2-oxopyrrolidin-1-yl)-4-phenylbutanoate; With lithium hydroxide; water; In tetrahydrofuran; for 16h;

With hydrogenchloride; In tetrahydrofuran; water; ethyl acetate;

Reference yield: 85.0%

C21H30N2O4 (658691-35-1) → (S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-4-phenylbutanoic acid (658691-36-2)

Guidance literature:

With lithium hydroxide; water; In tetrahydrofuran;

Reference yield: 100.0%

(S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-4-phenylbutanoic acid (658691-36-2) + (2R,4R)-tert-butyl 2-((1S,2S)-2-amino-1-(tert-butyldimethylsilyloxy)-3-(3,5-difluorophenyl)propyl)-4-hydroxypyrrolidine-1-carboxylate (877078-93-8) → (2R,4R)-tert-butyl 2-((1S,2S)-2-((S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-4-phenylbutanamido)-1-(tert-butyldimethylsilyloxy)-3-(3,5-difluorophenyl)propyl)-4-hydroxypyrrolidine-1-carboxylate (877078-88-1)

Guidance literature:

With 4-methyl-morpholine; HATU; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 2h;

upstream raw materials:

C₂₁H₃₀N₂O₄

Downstream raw materials:

(S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-N-((1S,2S)-1-((R)-1-benzhydrylpiperidin-2-yl)-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl)-4-phenylbutanamide

(S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-N-((1S,2S)-1-((R)-4-benzhydrylmorpholin-3-yl)-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl)-4-phenylbutanamide

(S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-N-((1S,2S)-1-((2R,4S)-1-benzhydryl-4-phenoxypyrrolidin-2-yl)-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl)-4-phenylbutanamide

(S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-N-((1S,2S)-1-((2R,4S)-1-benzhydryl-4-(pyridin-2-yloxy)pyrrolidin-2-yl)-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl)-4-phenylbutanamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 658691-36-2 (S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-4-phenylbutanoic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send