(S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-N-((1S,2S)-1-((R)-4-benzhydrylmorpholin-3-yl)-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl)-4-phenylbutanamide

Base Information

Chemical Name:(S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-N-((1S,2S)-1-((R)-4-benzhydrylmorpholin-3-yl)-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl)-4-phenylbutanamide
CAS No.:877079-38-4
Molecular Formula:C₄₆H₅₄F₂N₄O₅
Molecular Weight:780.955
Hs Code.:

(S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-N-((1S,2S)-1-((R)-4-benzhydrylmorpholin-3-yl)-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl)-4-phenylbutanamide

Synonyms:(S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-N-((1S,2S)-1-((R)-4-benzhydrylmorpholin-3-yl)-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl)-4-phenylbutanamide

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Chemical Property of (S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-N-((1S,2S)-1-((R)-4-benzhydrylmorpholin-3-yl)-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl)-4-phenylbutanamide

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Technology Process of (S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-N-((1S,2S)-1-((R)-4-benzhydrylmorpholin-3-yl)-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl)-4-phenylbutanamide

There total 1 articles about (S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-N-((1S,2S)-1-((R)-4-benzhydrylmorpholin-3-yl)-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl)-4-phenylbutanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 658691-36-2
(S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-4-phenylbutanoic acid

: 877078-87-0
(1S,2S)-2-Amino-1-((R)-4-benzhydrylmorpholin-3-yl)-3-(3,5-difluorophenyl)propan-1-ol

: 877079-38-4
(S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-N-((1S,2S)-1-((R)-4-benzhydrylmorpholin-3-yl)-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl)-4-phenylbutanamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; HATU; In dichloromethane;

Reference yield:

: 877079-38-4
(S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-N-((1S,2S)-1-((R)-4-benzhydrylmorpholin-3-yl)-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl)-4-phenylbutanamide

: (S)-2-((S)-3-acetamido-3-((S)-sec-butyl)-2-oxopyrrolidin-1-yl)-N-((1S,2S)-3-(3,5-difluorophenyl)-1-hydroxy-1-((R)-morpholin-3-yl)propan-2-yl)-4-phenylbutanamide

Guidance literature:: With hydrogen; acetic acid; palladium 10% on activated carbon; In methanol; for 3.5h; under 2585.81 Torr; Parr apparatus;