N-(2-ethoxy-2-oxoethyl)-N-(3-hydroxyphenyl)glycine ethyl ester

Base Information

• Chemical Name: N-(2-ethoxy-2-oxoethyl)-N-(3-hydroxyphenyl)glycine ethyl ester
• CAS No.: 1076193-33-3
• Molecular Formula: C₁₄H₁₉NO₅
• Molecular Weight: 281.309
• Mol file: 1076193-33-3.mol

Synonyms:N-(2-ethoxy-2-oxoethyl)-N-(3-hydroxyphenyl)glycine ethyl ester

Chemical Property of N-(2-ethoxy-2-oxoethyl)-N-(3-hydroxyphenyl)glycine ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2-ethoxy-2-oxoethyl)-N-(3-hydroxyphenyl)glycine ethyl ester

There total 1 articles about N-(2-ethoxy-2-oxoethyl)-N-(3-hydroxyphenyl)glycine ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

ethyl bromoacetate (105-36-2) + m-Hydroxyaniline (591-27-5) → N-(2-ethoxy-2-oxoethyl)-N-(3-hydroxyphenyl)glycine ethyl ester (1076193-33-3)

Guidance literature:

With ammonium dihydrogen phosphate; potassium iodide; In acetonitrile; for 4h; Reflux;

DOI:10.1021/ol802117p

Reference yield: 91.0%

N-(2-ethoxy-2-oxoethyl)-N-(3-hydroxyphenyl)glycine ethyl ester (1076193-33-3) + 2,5-dichloro-4-aminobenzenesulfonyl fluoride (5312-75-4) → C20H20Cl2FN3O7S

Guidance literature:

2,5-dichloro-4-aminobenzenesulfonyl fluoride; With acetic acid; propionic acid; at 20 ℃; for 0.5h;

With nitrosylsulfuric acid; at 0 - 5 ℃; for 1.33333h;

N-(2-ethoxy-2-oxoethyl)-N-(3-hydroxyphenyl)glycine ethyl ester; Further stages;

Reference yield: 87.0%

N-(2-ethoxy-2-oxoethyl)-N-(3-hydroxyphenyl)glycine ethyl ester (1076193-33-3) + 4-nitro-aniline (100-01-6,104810-17-5) → N-[3-hydroxy-4-[2-(4-nitrophenyl)diazenyl]phenyl]-N-(2-ethoxy-2-oxoethyl)glycine ethyl ester

Guidance literature:

4-nitro-aniline; With acetic acid; at 20 ℃; for 0.5h;

With hydrogenchloride; sodium nitrite; In water; at 0 - 5 ℃; for 1.33333h;

N-(2-ethoxy-2-oxoethyl)-N-(3-hydroxyphenyl)glycine ethyl ester; Further stages;

upstream raw materials:

ethyl bromoacetate

m-Hydroxyaniline

Downstream raw materials:

C₁₇H₁₉NO₆

2,2'-((4-formyl-3-hydroxyphenyl)azanediyl)diacetic acid

(E)-3-(4-dicarboxymethylamino-2-hydroxyphenyl)acrylic acid ethyl ester