Technology Process of (Z)-4-benzylidene-1-methyl-1,4-dihydro-2H-3,1-benzoxazine-2-one
There total 6 articles about (Z)-4-benzylidene-1-methyl-1,4-dihydro-2H-3,1-benzoxazine-2-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
silver nitrate; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
dimethyl sulfoxide;
at 20 ℃;
for 24h;
under 7500.75 Torr;
Autoclave;
DOI:10.1021/ol303534w
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: tetrahydrofuran / 48 h / 80 °C
2.1: sodium hydride / hexane; tetrahydrofuran / 1 h / 0 °C
2.2: 24 h / 20 °C
3.1: sulfuric acid / dichloromethane / 6 h / 0 - 20 °C
4.1: silver nitrate; 1,8-diazabicyclo[5.4.0]undec-7-ene / dimethyl sulfoxide / 24 h / 20 °C / 7500.75 Torr / Autoclave
With
sulfuric acid; sodium hydride; silver nitrate; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
tetrahydrofuran; hexane; dichloromethane; dimethyl sulfoxide;
DOI:10.1021/ol303534w
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / hexane; tetrahydrofuran / 1 h / 0 °C
1.2: 24 h / 20 °C
2.1: sulfuric acid / dichloromethane / 6 h / 0 - 20 °C
3.1: silver nitrate; 1,8-diazabicyclo[5.4.0]undec-7-ene / dimethyl sulfoxide / 24 h / 20 °C / 7500.75 Torr / Autoclave
With
sulfuric acid; sodium hydride; silver nitrate; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
tetrahydrofuran; hexane; dichloromethane; dimethyl sulfoxide;
DOI:10.1021/ol303534w