(3,4-Dimethoxybenzyl)hydrazine

Base Information

• Chemical Name: (3,4-Dimethoxybenzyl)hydrazine
• CAS No.: 135-85-3
• Molecular Formula: C9H14 N2 O2
• Molecular Weight: 182.25
• Hs Code.: 2928000090
• DSSTox Substance ID: DTXSID60159200
• Nikkaji Number: J3.023.115E
• Wikidata: Q83027520
• Mol file: 135-85-3.mol

Synonyms:3,4-dimethoxybenzylhydrazine;vetrazine;vetrazine monohydrochloride

Chemical Property of (3,4-Dimethoxybenzyl)hydrazine

Chemical Property:

• Vapor Pressure: 2.13E-09mmHg at 25°C
• Melting Point: 32-34 °C
• Refractive Index: 1.4922 (estimate)
• Boiling Point: 336.5°Cat760mmHg
• PKA: 7.07±0.70(Predicted)
• Flash Point: 157.3°C
• PSA: 56.51000
• Density: 1.096g/cm³
• LogP: 1.75830
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 182.105527694
• Heavy Atom Count: 13
• Complexity: 144

Purity/Quality:

98%Min ^*data from raw suppliers

(3,4-Dimethoxybenzyl)hydrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1)CNN)OC

Technology Process of (3,4-Dimethoxybenzyl)hydrazine

There total 2 articles about (3,4-Dimethoxybenzyl)hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-chloromethyl-1,2-dimethoxy-benzene (7306-46-9) → (3,4-dimethoxybenzyl)hydrazine (135-85-3)

Guidance literature:

With hydrazine hydrate;

Reference yield:

→ (3,4-dimethoxybenzyl)hydrazine (135-85-3)

Guidance literature:

Reference yield: 52.0%

(3,4-dimethoxybenzyl)hydrazine (135-85-3) + 1,1-diethoxy-3-isothiocyanatobutane (201872-43-7) → N-(3,3-diethoxy-1-methylpropyl)-2-(3,4-dimethoxybenzyl)hydrazine-1-carbothioamide

Guidance literature:

In diethyl ether;

DOI:10.1134/S107042800609003X

upstream raw materials:

4-chloromethyl-1,2-dimethoxy-benzene

Downstream raw materials:

Benzaldehyd-veratrylhydrazon