Ketoprofen amide

Base Information

Chemical Name:Ketoprofen amide
CAS No.:59512-16-2
Molecular Formula:C16H15NO2
Molecular Weight:253.301
Hs Code.:
UNII:50IY2AXR5Q
DSSTox Substance ID:DTXSID50974924
Nikkaji Number:J87.414K
Wikidata:Q27260795
Mol file:59512-16-2.mol

Synonyms:Ketoprofen amide;59512-16-2;rac Ketoprofen Amide;2-(3-benzoylphenyl)propanamide;(2RS)-2-(3-Benzoylphenyl)propanamide;BRN 2979493;2-(3-Benzoylphenyl)propionamide;Propionamide, 2-(3-benzoylphenyl)-;UNII-50IY2AXR5Q;50IY2AXR5Q;Benzeneacetamide, 3-benzoyl-.alpha.-methyl-;Ketoprofen Impurity E;SCHEMBL1887588;DTXSID50974924;KETOPROFEN AMIDE, (RS)-;KLWMCJJRUWWDSW-UHFFFAOYSA-N;KETOPROFEN AMIDE, (+/-)-;2-(3-Benzoylphenyl)propanimidic acid;KETOPROFEN IMPURITY E [EP IMPURITY];LS-124047;FT-0670652;Q27260795

Suppliers and Price of Ketoprofen amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
racKetoprofenAmide
250mg
$ 180.00

Total 14 raw suppliers

Chemical Property of Ketoprofen amide

Chemical Property:

Vapor Pressure:5.59E-09mmHg at 25°C
Melting Point:102 - 107°C
Boiling Point:469.3°C at 760 mmHg
PKA:16.03±0.50(Predicted)
Flash Point:237.6°C
PSA：61.15000
Density:1.159g/cm³
LogP:3.65610
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:253.110278721
Heavy Atom Count:19
Complexity:334

Purity/Quality:

99%, ^*data from raw suppliers

racKetoprofenAmide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC(=CC=C1)C(=O)C2=CC=CC=C2)C(=O)N
Uses An amide of Ketoprofen (K200800) with anti-inflammatory properties.

Technology Process of Ketoprofen amide

There total 4 articles about Ketoprofen amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 22071-15-4,22161-86-0
ketoprofen

: 59512-16-2
3-benzoyl-α-methylbenzeneacetamide

Guidance literature:: With tris[2-phenylpyridinato-C₂,N]iridium(III); dipotassium hydrogenphosphate; borane-ammonia complex; di-tert-butyl dicarbonate; magnesium chloride; In acetonitrile; at 20 ℃; for 36h; Schlenk technique; Irradiation; Green chemistry;
DOI:10.1039/d1gc01157j

Reference yield: 73.0%

: 42872-30-0
alpha-(m-benzoylphenyl)propionitrile

: 59512-16-2
3-benzoyl-α-methylbenzeneacetamide

Guidance literature:: With Os(hydride)6(triisopropylphosphine)2; water; In tetrahydrofuran-d8; at 100 ℃; for 4h; Inert atmosphere;
DOI:10.1021/acs.inorgchem.1c00380