(1R,2R)-2-amino-1-(4-chlorophenyl)propane-1,3-diol

Base Information

Chemical Name:(1R,2R)-2-amino-1-(4-chlorophenyl)propane-1,3-diol
CAS No.:911444-78-5
Molecular Formula:C₉H₁₂ClNO₂
Molecular Weight:201.653
Hs Code.:

Synonyms:(1R,2R)-2-amino-1-(4-chlorophenyl)propane-1,3-diol

Suppliers and Price of (1R,2R)-2-amino-1-(4-chlorophenyl)propane-1,3-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (1R,2R)-2-amino-1-(4-chlorophenyl)propane-1,3-diol

Chemical Property:

Purity/Quality:: ≥98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of (1R,2R)-2-amino-1-(4-chlorophenyl)propane-1,3-diol

There total 7 articles about (1R,2R)-2-amino-1-(4-chlorophenyl)propane-1,3-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 338-69-2,25191-17-7,18875-37-1
D-Alanine

: 104-88-1
4-chlorobenzaldehyde

: 911444-78-5
(1R,2R)-2-amino-1-(4-chlorophenyl)propane-1,3-diol

Guidance literature:: 4-chlorobenzaldehyde; With thiamine pyrophosphate; E_. coli transketolase 1_YYF mutant; lithium hydroxypyruvate; magnesium chloride; In aq. buffer; at 25 ℃; pH=7.5;

D-Alanine; With glucose dehydrogenase; D-Glucose; pyridoxal 5'-phosphate; arthrobacter sp. ω-transaminase 117_ACHH mutant; nicotinamide-adenine dinucleotide; lactate dehydrogenase; In aq. buffer; at 25 ℃; for 3h; pH=7.5;
DOI:10.1021/acscatal.1c01229

Reference yield:

: (+1-)ethyl (2S,3R)-2-amino-3-(4-chlorophenyl)-3-hydroxypropanoate

: 911444-78-5
(1R,2R)-2-amino-1-(4-chlorophenyl)propane-1,3-diol

Guidance literature:: (+1-)ethyl (2S,3R)-2-amino-3-(4-chlorophenyl)-3-hydroxypropanoate; With (S)-Mandelic acid; In ethanol; at 35 - 40 ℃;

With methanol; potassium borohydride; at 40 ℃; for 6h;