4’-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1’-biphenyl]-2-carboxylicacid

Base Information

Chemical Name:4’-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1’-biphenyl]-2-carboxylicacid
CAS No.:133141-63-6
Molecular Formula:C₂₄H₂₂N₂O₂
Molecular Weight:370.451
Hs Code.:

Synonyms:4’-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1’-biphenyl]-2-carboxylicacid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4’-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1’-biphenyl]-2-carboxylicacid

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Technology Process of 4’-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1’-biphenyl]-2-carboxylicacid

There total 12 articles about 4’-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1’-biphenyl]-2-carboxylicacid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.2%

: 133224-92-7
tert.butyl 4'-[(2-n-propyl-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylate

: 133141-63-6
4’-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1’-biphenyl]-2-carboxylicacid

Guidance literature:: With trifluoroacetic acid;

Reference yield: 85.0%

: 4’-((2-propyl-1H-benzo[d]imidazole-1-yl)methyl)-[1,1’-biphenyl]-2-carboxylic acid methyl ester

: 133141-63-6
4’-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1’-biphenyl]-2-carboxylicacid

Guidance literature:: With sodium hydroxide; In methanol; for 12h; Reflux;
DOI:10.1016/j.ejmech.2016.08.027

Reference yield: 43.0%

: 136285-23-9
4’-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile

: 133141-63-6
4’-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1’-biphenyl]-2-carboxylicacid

Guidance literature:: 4'-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile; With water; potassium hydroxide; In ethylene glycol; at 185 ℃;

With hydrogenchloride; In water; ethylene glycol; at 100 ℃; for 0.25h; pH=5 - 6;
DOI:10.1016/j.bmc.2010.06.102