{3-[(4-chlorophenyl)(2-methylpyridin-3-yl)methoxy]azetidin-1-yl}piperidin-1-ylmethanone

Base Information

Chemical Name:{3-[(4-chlorophenyl)(2-methylpyridin-3-yl)methoxy]azetidin-1-yl}piperidin-1-ylmethanone
CAS No.:1357305-46-4
Molecular Formula:C₂₂H₂₆ClN₃O₂
Molecular Weight:399.92
Hs Code.:

Synonyms:{3-[(4-chlorophenyl)(2-methylpyridin-3-yl)methoxy]azetidin-1-yl}piperidin-1-ylmethanone

Suppliers and Price of {3-[(4-chlorophenyl)(2-methylpyridin-3-yl)methoxy]azetidin-1-yl}piperidin-1-ylmethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of {3-[(4-chlorophenyl)(2-methylpyridin-3-yl)methoxy]azetidin-1-yl}piperidin-1-ylmethanone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of {3-[(4-chlorophenyl)(2-methylpyridin-3-yl)methoxy]azetidin-1-yl}piperidin-1-ylmethanone

There total 5 articles about {3-[(4-chlorophenyl)(2-methylpyridin-3-yl)methoxy]azetidin-1-yl}piperidin-1-ylmethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 110-89-4
piperidine

: C₁₇H₁₆Cl₂N₂O₂

: 1357305-46-4
{3-[(4-chlorophenyl)(2-methylpyridin-3-yl)methoxy]azetidin-1-yl}piperidin-1-ylmethanone

Guidance literature:: With triethylamine; In dichloromethane; for 1h;
DOI:10.1016/j.bmcl.2011.12.032

Reference yield:

: 60032-57-7
2-methylnicotinaldehyde

: 1357305-46-4
{3-[(4-chlorophenyl)(2-methylpyridin-3-yl)methoxy]azetidin-1-yl}piperidin-1-ylmethanone

Guidance literature:: Multi-step reaction with 4 steps

1: tetrahydrofuran; diethyl ether / 0.5 h / 20 °C / Inert atmosphere

2: toluene-4-sulfonic acid / 10 h / 145 °C

3: pyridine / dichloromethane / 1.5 h / 0 - 20 °C

4: triethylamine / dichloromethane / 1 h

With pyridine; toluene-4-sulfonic acid; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1016/j.bmcl.2011.12.032

Reference yield:

: 1357306-00-3
3-(4-chlorophenyl-2-methylpyrid-3ylmethoxy)azetidine

: 1357305-46-4
{3-[(4-chlorophenyl)(2-methylpyridin-3-yl)methoxy]azetidin-1-yl}piperidin-1-ylmethanone

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 1.5 h / 0 - 20 °C

2: triethylamine / dichloromethane / 1 h

With pyridine; triethylamine; In dichloromethane;
DOI:10.1016/j.bmcl.2011.12.032