60032-57-7

Basic information

• Product Name: 2-METHYLNICOTINALDEHYDE
• Synonyms: 2-METHYLNICOTINALDEHYDE;2-Methylpyridine-3-carbaldehyde;2-Methylpyridine-3-carboxaldehyde;2-Methylpyridine-3-carbox...;3-Pyridinecarboxaldehyde, 2-Methyl-;2-Methyl-3-Pyridinecarboxaldehyde
• CAS NO: 60032-57-7
• Molecular Formula: C₇H₇NO
• Molecular Weight: 121.14
• Product Categories: Pyridines
• Mol File: 60032-57-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 242 °C (decomp)
• Boiling Point: 211.886 °C at 760 mmHg
• Flash Point: 93℃
• Appearance: /
• Density: 1.106 g/mL at 25 °C
• Vapor Pressure: 0.178mmHg at 25°C
• Refractive Index: n20/D1.549
• PKA: 4.15±0.10(Predicted)
• CAS DataBase Reference: 2-METHYLNICOTINALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYLNICOTINALDEHYDE(60032-57-7)
• EPA Substance Registry System: 2-METHYLNICOTINALDEHYDE(60032-57-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• WGK Germany: 3
• Hazardous Substances Data: 60032-57-7(Hazardous Substances Data)

Usage

Uses

2-Methylnicotinaldehyde is a useful research chemical.

InChI:InChI=1/C7H7NO/c1-6-7(5-9)3-2-4-8-6/h2-5H,1H3

Upstream product

• 583-61-9 2,3-Lutidine 
• 68-12-2 N,N-dimethyl-formamide 
• 38749-79-0 3-bromo-2-picoline 

Downstream Products

• 1026463-10-4 [2'-(4,4-Dimethyl-4,5-dihydro-oxazol-2-yl)-biphenyl-4-yl]-(2-methyl-pyridin-3-yl)-methanol 
• 335428-90-5 3-(difluoromethyl)-2-methylpyridine 
• 190249-18-4 2-Methyl-3-formylpyridine cyanohydrin 
• 154650-88-1 methyl thieno[2,3-b]pyridine-2-carboxylate 
• 1263137-17-2 C₂₁H₁₇N₃O₂ 
• 159892-20-3 2-amino-2-(2-methylpyridin-3-yl)acetonitrile 
• 1422167-03-0 C₃₂H₃₀N₂O₂ 
• 1422167-02-9 C₃₁H₂₇ClN₂O₂ 
• 56826-61-0 (2-methylpyridin-3-yl)methanol 
• 1421928-97-3 methyl 2-(2-(((2-methylpyridin-3-yl)methyl)amino)thiazol-4-yl)acetate 
• 1421928-11-1 C₂₉H₂₇ClN₂O₂ 
• 1421928-60-0 2-(4-((2-methylpyridin-3-yl)methoxy)phenyl)acetic acid hydrochloride 
• 1421928-59-7 ethyl 2-(4-((2-methylpyridin-3-yl)methoxy)phenyl)acetate 
• 120277-68-1 2-methyl-3-(chloromethyl)pyridine 

Relevant articles and documents

BENZIMIDAZOLES AND RELATED ANALOGS AS SIRTUIN MODULATORS

Provided herein are sirtuin-modulating compounds of formula (II) The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.

REACTIVITY OF METHYL DERIVATIVES OF NITROGENOUS HETEROCYCLES IN VAPOR-PHASE CATALYTIC OXIDATION

A study has been made of the reactivity of methylpyridines, methylpyrazines, and methylquinolines in oxidation in the vapor phase in the presence of β-VO(PO3)2.Relationships have been found between the overall reaction rates of heterocyclic compounds and the charge on the ring nitrogen, and between the partial oxidation rate and the charge on the ring carbon atom adjacent to the methyl group.The partial oxidation rate of methylpyridines is given to a first approximation by the Hammett-type expression lnWa = -3.5 + 4.6 Σ?, with a correlation coefficient of 0.93.