5-trifluoromethyl-3'-O-(3-carboxypropionyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine

Base Information

Chemical Name:5-trifluoromethyl-3'-O-(3-carboxypropionyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine
CAS No.:1046113-67-0
Molecular Formula:C₃₅H₃₃F₃N₂O₁₀
Molecular Weight:698.65
Hs Code.:

Synonyms:5-trifluoromethyl-3'-O-(3-carboxypropionyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-trifluoromethyl-3'-O-(3-carboxypropionyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine

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Technology Process of 5-trifluoromethyl-3'-O-(3-carboxypropionyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine

There total 2 articles about 5-trifluoromethyl-3'-O-(3-carboxypropionyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-30-5
succinic acid anhydride

: 133128-06-0
5'-O-(4,4'-dimethoxytrityl)-α,α,α-trifluorothymidine

: 1046113-67-0
5-trifluoromethyl-3'-O-(3-carboxypropionyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine

Guidance literature:: With dmap; triethylamine; In dichloromethane; for 12h;

Reference yield:

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 70-00-8
2'-deoxy-5-trifluoromethyluridine

: 1046113-67-0
5-trifluoromethyl-3'-O-(3-carboxypropionyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; pyridine / 21 h / 0 - 20 °C

2: dmap; triethylamine / dichloromethane / 12 h

With pyridine; dmap; triethylamine; In dichloromethane;