tert-butyl (R)-4-((3-(bis-(benzyloxy)phosphoryloxy)phenoxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate

Base Information

• Chemical Name: tert-butyl (R)-4-((3-(bis-(benzyloxy)phosphoryloxy)phenoxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate
• CAS No.: 1239586-99-2
• Molecular Formula: C₃₁H₃₈NO₈P
• Molecular Weight: 583.618
• Mol file: 1239586-99-2.mol

Synonyms:tert-butyl (R)-4-((3-(bis-(benzyloxy)phosphoryloxy)phenoxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate

Chemical Property of tert-butyl (R)-4-((3-(bis-(benzyloxy)phosphoryloxy)phenoxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl (R)-4-((3-(bis-(benzyloxy)phosphoryloxy)phenoxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate

There total 1 articles about tert-butyl (R)-4-((3-(bis-(benzyloxy)phosphoryloxy)phenoxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

Dibenzyl phosphite (17176-77-1) + tert-butyl (R)-4-((3-hydroxyphenoxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate (1239586-93-6) → tert-butyl (R)-4-((3-(bis-(benzyloxy)phosphoryloxy)phenoxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate (1239586-99-2)

Guidance literature:

With carbon tetrabromide; sodium hydroxide; In dichloromethane; water; at 20 ℃; Cooling with ice;

DOI:10.1590/S0103-50532010000400014

Reference yield:

tert-butyl (R)-4-((3-(bis-(benzyloxy)phosphoryloxy)phenoxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate (1239586-99-2) → C17H26NO8P

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; at 20 ℃; for 1h; under 2068.65 Torr;

DOI:10.1590/S0103-50532010000400014

upstream raw materials:

Dibenzyl phosphite

tert-butyl (R)-4-((3-hydroxyphenoxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate