N-(4-methylphenyl)-1-imino-(4-methylphenyl)isoindoline

Base Information

• Chemical Name: N-(4-methylphenyl)-1-imino-(4-methylphenyl)isoindoline
• CAS No.: 1093076-02-8
• Molecular Formula: C₂₂H₂₀N₂
• Molecular Weight: 312.414
• Mol file: 1093076-02-8.mol

Synonyms:N-(4-methylphenyl)-1-imino-(4-methylphenyl)isoindoline

Chemical Property of N-(4-methylphenyl)-1-imino-(4-methylphenyl)isoindoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-methylphenyl)-1-imino-(4-methylphenyl)isoindoline

There total 1 articles about N-(4-methylphenyl)-1-imino-(4-methylphenyl)isoindoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

p-toluidine (106-49-0,12221-03-3) + o-phthalic dicarboxaldehyde (643-79-8) → N-(4-methylphenyl)-1-imino-(4-methylphenyl)isoindoline (1093076-02-8)

Guidance literature:

With formic acid; In diethyl ether; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1039/b806544f

Reference yield: 46.0%

N-(4-methylphenyl)-1-imino-(4-methylphenyl)isoindoline (1093076-02-8) + palladium diacetate (3375-31-3) → bis(μ-acetato)(1-p-methylphenylimino-2-p-methylphenylisoindoline)dipalladium(II) (1093076-07-3,1093415-77-0)

Guidance literature:

In dichloromethane; under N2 atm. soln. Pd(OAc)2 and iminoisoindoline in CH2Cl2 was stirred at room temp. for 12 h; soln. was filtered and concd., ether was added, ppt. was filtered, washed with cold ether and dried in vacuo; elem. anal.;

DOI:10.1039/b806544f

Reference yield:

N-(4-methylphenyl)-1-imino-(4-methylphenyl)isoindoline (1093076-02-8) → bis(μ-acetato)(1-p-methylphenylimino-2-p-methylphenylisoindoline)dipalladium(II)*CHCl3 (1093415-73-6)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane

2: chloroform

In dichloromethane; chloroform;

DOI:10.1039/b806544f

upstream raw materials:

p-toluidine

o-phthalic dicarboxaldehyde

Downstream raw materials:

bis(μ-acetato)(1-p-methylphenylimino-2-p-methylphenylisoindoline)dipalladium(II)

bis(μ-acetato)(1-p-methylphenylimino-2-p-methylphenylisoindoline)dipalladium(II)*CHCl3

Refernces

• 1、 Chitanda, Jackson M.,Prokopchuk, Demyan E.,Quail, J. Wilson,Foley, Stephen R.. "Synthesis of palladacycles employing iminoisoindolines as monoanionic bidentate ligands". experimental part. p. 6023 - 6029. Retrieved 2009/02/08.