Palladium (II) Acetate

Base Information

• Chemical Name: Palladium (II) Acetate
• CAS No.: 3375-31-3
• Molecular Formula: C4H8O4Pd
• Molecular Weight: 673.528
• Hs Code.: 28439090
• Mol file: 3375-31-3.mol

Synonyms:Aceticacid, palladium(2+) salt (8CI,9CI);Palladium acetate (Pd(OAc)2)(7CI);Acetic acid palladium salt;Bis(acetato)palladium;Diacetatopalladium;Diacetoxypalladium;Palladium acetate (Pd(OCOCH3)2);Palladium(2+) acetate;Palladium(2+) diacetate;Palladium(II) acetate;Palladous acetate;Acetic acid, palladium(2+) salt (2:1);palladium acetate;Palladium(2+) diacetate;palladium(ii) acetate;palladium(II)-acetate;

Chemical Property of Palladium (II) Acetate

Chemical Property:

• Appearance/Colour: brown needles
• Vapor Pressure: 0.002Pa at 25℃
• Melting Point: 205 °C
• Boiling Point: 117.1 °C at 760 mmHg
• Flash Point: 40 °C
• PSA: 80.26000
• LogP: -2.48760
• Storage Temp.: Store at R.T.
• Sensitive.: Hygroscopic
• Solubility.: Soluble as monomer in glacial acetic acid or as trimer in benzen
• Water Solubility.: insoluble

Purity/Quality:

98% ^*data from raw suppliers

Palladium(II) Acetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi; Xn
• Hazard Codes: Xi,Xn,C
• Statements: 41-36/37/38-40-35
• Safety Statements: 26-39-36/37/39-45-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: suzuki reaction Palladium (II) Acetate Trimer is used in Suzuki-Miyaura cross-coupling reactions. It also serves to catalyze the chemoselective reduction of nitroarenes. A catalyst for intramolecular coupling.

Technology Process of Palladium (II) Acetate

There total 26 articles about Palladium (II) Acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

palladium (7440-05-3) + acetic acid (64-19-7,77671-22-8) → palladium diacetate (3375-31-3)

Guidance literature:

With nitric acid; In nitric acid; acetic acid; boiling Pd-sponge in mixt. of glacial AcOH and concd. HNO3 (100:3 v/v), addn. of further Pd to end of evolution of N-oxides (if necessary); hot filtration, cooling (crystn.), washing (AcOH, water), drying in air;

DOI:10.1016/S0020-1693(99)00276-5

Reference yield: 90.0%

palladium (II) nitrate + acetic acid (64-19-7,77671-22-8) → palladium diacetate (3375-31-3)

Guidance literature:

for 24h; Inert atmosphere; Reflux;

DOI:10.1021/acs.orglett.5b02835

Reference yield: 85.0%

trans-dinitratodiaquapalladium(II) (82279-70-7,1147543-08-5) + acetic acid (64-19-7,77671-22-8) → palladium diacetate (3375-31-3)

Guidance literature:

In acetic acid; Pd(II) nitrate dissolved in anhyd. acetic acid; stirred for 3 h at room temp.; suspn. diluted with acetic acid; centrifuged; washed (H2O, acetone); dried (vac., NaOH); elem. anal.;

DOI:10.1134/S003602361110024X

upstream raw materials:

acetic acid

palladium

[bis(acetoxy)iodo]benzene

palladium(II) iodide

Downstream raw materials:

methyl 2-<1-acetoxy-6-(p-tolylsulfonamido)hexyl>acrylate

N,2,4-trimethylaniline

4-(N,N-dimethylamino)-3-methylbenzyl acetate

N,N,2,4-tetramethyl-6-acetoxyaniline

Refernces

• 1、 Stolyarov,Demina,Cherkashina. "Preparative synthesis of palladium(II) acetate: Reactions, intermediates, and by-products". . p. 1532 - 1537. Retrieved 2011.
• 2、 Mulagaleev,Kirik. "Palladium(II) acetates: Synthesis and molecular transformation scheme". . p. 2065 - 2075. Retrieved 2010.
• 3、 Ahmed Fouad, Manar,Ferretti, Francesco,Formenti, Dario,Milani, Fabio,Ragaini, Fabio. "Synthesis of Indoles by Reductive Cyclization of Nitro Compounds Using Formate Esters as CO Surrogates". supporting information. p. 4876 - 4894. Retrieved 2021/09/20.
• 4、 Zang, Ying-Da,Li, Chuang-Jun,Song, Xiu-Yun,Ma, Jie,Yang, Jing-Zhi,Chen, Nai-Hong,Zhang, Dong-Ming. "Total synthesis and neuroprotective effect of O-methylmurrayamine A and 7-methoxymurrayacine". . p. 623 - 629. Retrieved 2017/05/26.