C₁₄H₁₈BrNO₃

Base Information

• Chemical Name: C₁₄H₁₈BrNO₃
• CAS No.: 1431556-76-1
• Molecular Formula: C₁₄H₁₈BrNO₃
• Molecular Weight: 328.206
• Mol file: 1431556-76-1.mol

Synonyms:C₁₄H₁₈BrNO₃

Chemical Property of C₁₄H₁₈BrNO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₈BrNO₃

There total 3 articles about C₁₄H₁₈BrNO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl (1-(4-bromophenyl)-3-hydroxypropan-2-yl)carbamate (1333114-52-5) → C14H18BrNO3 (1431556-76-1)

Guidance literature:

With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; trichloroisocyanuric acid; In dichloromethane; at 0 ℃; for 0.333333h;

Reference yield:

p-bromo-DL-phenylalanine (14091-15-7) → C14H18BrNO3 (1431556-76-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium tetrahydroborate / tetrahydrofuran / 0.5 h / 0 °C

1.2: 30.5 h / Cooling with ice; Reflux

2.1: methanol / 1.5 h / 50 °C / Cooling with ice

3.1: trichloroisocyanuric acid; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / dichloromethane / 0.33 h / 0 °C

With sodium tetrahydroborate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; trichloroisocyanuric acid; In tetrahydrofuran; methanol; dichloromethane;

Reference yield:

2-amino-3-(4-bromophenyl)propanol (86886-33-1) → C14H18BrNO3 (1431556-76-1)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol / 1.5 h / 50 °C / Cooling with ice

2: trichloroisocyanuric acid; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / dichloromethane / 0.33 h / 0 °C

With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; trichloroisocyanuric acid; In methanol; dichloromethane;

upstream raw materials:

p-bromo-DL-phenylalanine

2-amino-3-(4-bromophenyl)propanol

tert-butyl (1-(4-bromophenyl)-3-hydroxypropan-2-yl)carbamate