6-methoxy-5-phenyl-[8]quinolylamine

Base Information

• Chemical Name: 6-methoxy-5-phenyl-[8]quinolylamine
• CAS No.: 705928-24-1
• Molecular Formula: C₁₆H₁₄N₂O
• Molecular Weight: 250.3
• Mol file: 705928-24-1.mol

Synonyms:6-methoxy-5-phenyl-[8]quinolylamine

Chemical Property of 6-methoxy-5-phenyl-[8]quinolylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-methoxy-5-phenyl-[8]quinolylamine

There total 5 articles about 6-methoxy-5-phenyl-[8]quinolylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

6-methoxy-8-nitro-5-phenyl-quinoline (855760-31-5) → 6-methoxy-5-phenyl-[8]quinolylamine (705928-24-1)

Guidance literature:

With hydrogenchloride; tin; tin(ll) chloride; In water; at 0 ℃; for 1h;

DOI:10.1016/j.ejmech.2018.02.048

Reference yield:

N-Acetyl-2-methoxy-5-aminobiphenyl (146474-25-1) → 6-methoxy-5-phenyl-[8]quinolylamine (705928-24-1)

Guidance literature:

Multi-step reaction with 3 steps

1: water; acetic acid; nitric acid

2: glycerol; arsenic (V)-oxide; concentrated sulfuric acid / 170 °C

3: platinum; acetic acid / Hydrogenation

With arsenic(V) oxide; sulfuric acid; water; nitric acid; acetic acid; glycerol; platinum;

DOI:10.1021/ja01212a047

Reference yield:

N-(6-methoxy-4-nitro-biphenyl-3-yl)-acetamide (500344-73-0) → 6-methoxy-5-phenyl-[8]quinolylamine (705928-24-1)

Guidance literature:

Multi-step reaction with 2 steps

1: glycerol; arsenic (V)-oxide; concentrated sulfuric acid / 170 °C

2: platinum; acetic acid / Hydrogenation

With arsenic(V) oxide; sulfuric acid; acetic acid; glycerol; platinum;

DOI:10.1021/ja01212a047

upstream raw materials:

6-methoxy-8-nitro-5-phenyl-quinoline

N-Acetyl-2-methoxy-5-aminobiphenyl

N-(6-methoxy-4-nitro-biphenyl-3-yl)-acetamide

6-methoxy-8-nitroquinoline