1-Chloro-3-ethoxypropan-2-one

Base Information

• Chemical Name: 1-Chloro-3-ethoxypropan-2-one
• CAS No.: 69378-63-8
• Molecular Formula: C₅H₉ClO₂
• Molecular Weight: 136.578
• European Community (EC) Number: 970-738-4
• Mol file: 69378-63-8.mol

Synonyms:1-chloro-3-ethoxypropan-2-one;69378-63-8;1-chloro-3-(ethoxy)acetone;SCHEMBL4293834;GRKKNKUHYNPYKG-UHFFFAOYSA-N;AKOS006383250;CS-0375012;EN300-153280

Chemical Property of 1-Chloro-3-ethoxypropan-2-one

Chemical Property:

• XLogP3: 0.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 136.0291072
• Heavy Atom Count: 8
• Complexity: 72.8

Purity/Quality:

99% ^*data from raw suppliers

1-Chloro-3-ethoxypropan-2-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOCC(=O)CCl

Technology Process of 1-Chloro-3-ethoxypropan-2-one

There total 1 articles about 1-Chloro-3-ethoxypropan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-ethoxy-3-chloro-propan-2-ol (4151-98-8) → 1-chloro-3-ethoxypropan-2-one (69378-63-8)

Guidance literature:

With chromium; acetic acid; at 50 ℃;

Reference yield: 90.0%

1-ethynyl-4-fluorobenzene (766-98-3) + 1-chloro-3-ethoxypropan-2-one (69378-63-8) → C13H14FN3O2

Guidance literature:

With silica coated copper nano-magnetite NHC-benzimi(at)Cu complex catalyst; In ethanol; at 80 ℃; for 0.5h;

DOI:10.1007/s10562-021-03772-9

Reference yield: 85.0%

1-chloro-3-ethoxypropan-2-one (69378-63-8) + 1-Ethynylcyclohexan-1-ol (78-27-3) → C13H21N3O3

Guidance literature:

With sodium azide; sodium L-ascorbate; In ethanol; at 80 ℃; for 0.333333h; Green chemistry;

DOI:10.1016/j.tetlet.2018.08.045

upstream raw materials:

1-ethoxy-3-chloro-propan-2-ol