(3R,4'S,5'S)-1-tert-butyl 4',5'-diethyl 5-methyl-2-oxo-5'-phenyl-4',5'-dihydrospiro[indoline-3,3'-pyrrole]-1,4',5'-tricarboxylate

Base Information

Chemical Name:(3R,4'S,5'S)-1-tert-butyl 4',5'-diethyl 5-methyl-2-oxo-5'-phenyl-4',5'-dihydrospiro[indoline-3,3'-pyrrole]-1,4',5'-tricarboxylate
CAS No.:1376607-17-8
Molecular Formula:C₂₉H₃₂N₂O₇
Molecular Weight:520.582
Hs Code.:

Synonyms:(3R,4'S,5'S)-1-tert-butyl 4',5'-diethyl 5-methyl-2-oxo-5'-phenyl-4',5'-dihydrospiro[indoline-3,3'-pyrrole]-1,4',5'-tricarboxylate

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Chemical Property of (3R,4'S,5'S)-1-tert-butyl 4',5'-diethyl 5-methyl-2-oxo-5'-phenyl-4',5'-dihydrospiro[indoline-3,3'-pyrrole]-1,4',5'-tricarboxylate

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Technology Process of (3R,4'S,5'S)-1-tert-butyl 4',5'-diethyl 5-methyl-2-oxo-5'-phenyl-4',5'-dihydrospiro[indoline-3,3'-pyrrole]-1,4',5'-tricarboxylate

There total 1 articles about (3R,4'S,5'S)-1-tert-butyl 4',5'-diethyl 5-methyl-2-oxo-5'-phenyl-4',5'-dihydrospiro[indoline-3,3'-pyrrole]-1,4',5'-tricarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 5-methyl-N-boc-methyleneindolinone

: 39533-31-8
ethyl α-phenylisocyanoacetate

: 1376607-65-6
1-tert-butyl 4′,5′-diethyl (3R,4′S,5′R)-5-methyl-2-oxo-5′-phenyl-4′,5′-dihydrospiro[indoline-3,3′-pyrrole]-1,4′,5′-tricarboxylate

: 1376607-17-8
(3R,4'S,5'S)-1-tert-butyl 4',5'-diethyl 5-methyl-2-oxo-5'-phenyl-4',5'-dihydrospiro[indoline-3,3'-pyrrole]-1,4',5'-tricarboxylate

Guidance literature:: With C₂₉H₂₈F₆N₄OS; In chloroform; at -20 ℃; for 23h; optical yield given as %ee; stereoselective reaction; Molecular sieve;
DOI:10.1039/c2cc30746d