Technology Process of (4-oxocyclohexyl)acetaldehyde
There total 6 articles about (4-oxocyclohexyl)acetaldehyde which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
oxalyl dichloride; dimethyl sulfoxide; triethylamine;
In
dichloromethane;
at -78 ℃;
for 0.5h;
DOI:10.1021/ol051569d
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 64 percent / H2 / 10percent Pd/C / ethyl acetate / 19 h
2: PCC, Florisil / CH2Cl2 / 4 h / Ambient temperature
With
florisil; hydrogen; pyridinium chlorochromate;
palladium on activated charcoal;
In
dichloromethane; ethyl acetate;
DOI:10.1021/ja00071a024
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 100 percent / NaH / tetrahydrofuran / 0.67 h / 0 °C
2: 100 percent / H2 / Pd/C / ethyl acetate / 2 h / 20 °C / atmospheric pressure
3: 100 percent / LiAlH4 / tetrahydrofuran / 4 h / 20 °C
4: 97 percent / aq. HCl / tetrahydrofuran / 24 h / 20 °C
5: 80 percent / (COCl)2; DMSO; Et3N / CH2Cl2 / 0.5 h / -78 °C
With
hydrogenchloride; lithium aluminium tetrahydride; oxalyl dichloride; hydrogen; sodium hydride; dimethyl sulfoxide; triethylamine;
palladium on activated charcoal;
In
tetrahydrofuran; dichloromethane; ethyl acetate;
1: Horner-Wadsworth-Emmons reaction / 5: Swern oxidation;
DOI:10.1021/ol051569d
