Technology Process of C19H20
There total 4 articles about C19H20 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(E)-7-methoxy-4,4-diphenylhepta-1,5-diene;
With
Schwartz's reagent;
In
dichloromethane;
at 20 ℃;
Inert atmosphere;
With
trimethylsilyl trifluoromethanesulfonate;
In
dichloromethane;
at 0 ℃;
for 1h;
Inert atmosphere;
DOI:10.1021/ol500400s
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / -20 °C / Inert atmosphere
1.2: -78 - 20 °C / Inert atmosphere
2.1: diisobutylaluminium hydride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere
2.2: 0.25 h / 20 °C / Inert atmosphere
3.1: sodium hydride / tetrahydrofuran / 0.5 h / Inert atmosphere
3.2: 1 h / Inert atmosphere
4.1: Schwartz's reagent / dichloromethane / 20 °C / Inert atmosphere
4.2: 1 h / 0 °C / Inert atmosphere
With
Schwartz's reagent; n-butyllithium; sodium hydride; diisobutylaluminium hydride;
In
tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/ol500400s
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: diisobutylaluminium hydride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere
1.2: 0.25 h / 20 °C / Inert atmosphere
2.1: sodium hydride / tetrahydrofuran / 0.5 h / Inert atmosphere
2.2: 1 h / Inert atmosphere
3.1: Schwartz's reagent / dichloromethane / 20 °C / Inert atmosphere
3.2: 1 h / 0 °C / Inert atmosphere
With
Schwartz's reagent; sodium hydride; diisobutylaluminium hydride;
In
tetrahydrofuran; dichloromethane;
DOI:10.1021/ol500400s
