2-(4-(methoxycarbonylmethylaminocarbonyl)phenyl)-N-methoxycarbonylmethyl-acrylamide

Base Information

• Chemical Name: 2-(4-(methoxycarbonylmethylaminocarbonyl)phenyl)-N-methoxycarbonylmethyl-acrylamide
• CAS No.: 1167996-48-6
• Molecular Formula: C₁₆H₁₈N₂O₆
• Molecular Weight: 334.329
• Mol file: 1167996-48-6.mol

Synonyms:2-(4-(methoxycarbonylmethylaminocarbonyl)phenyl)-N-methoxycarbonylmethyl-acrylamide

Chemical Property of 2-(4-(methoxycarbonylmethylaminocarbonyl)phenyl)-N-methoxycarbonylmethyl-acrylamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2-(4-(methoxycarbonylmethylaminocarbonyl)phenyl)-N-methoxycarbonylmethyl-acrylamide

There total 1 articles about 2-(4-(methoxycarbonylmethylaminocarbonyl)phenyl)-N-methoxycarbonylmethyl-acrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

carbon monoxide (201230-82-2) + glycine ethyl ester hydrochloride (5680-79-5,883886-67-7) + 1-(4-fluorophenyl)-1-iodoethene → 2-(4-iodo-phenyl)-N-(methoxycarbonylmethyl)acrylamide (1167996-52-2) + 2-(4-(methoxycarbonylmethylaminocarbonyl)phenyl)-N-methoxycarbonylmethyl-acrylamide (1167996-48-6)

Guidance literature:

With palladium diacetate; triethylamine; triphenylphosphine; In N,N-dimethyl-formamide; at 50 ℃; for 24h; under 30003 Torr;

DOI:10.1016/j.tet.2009.04.012

upstream raw materials:

carbon monoxide

glycine ethyl ester hydrochloride