2',3'-di-O-(tert-butyldimethylsilyl)-5'-O-[N-(L-phenylalanyl)-sulfamoyl]adenosine triethylamine salt

Base Information

Chemical Name:2',3'-di-O-(tert-butyldimethylsilyl)-5'-O-[N-(L-phenylalanyl)-sulfamoyl]adenosine triethylamine salt
CAS No.:1122489-91-1
Molecular Formula:C₆H₁₅N*C₃₁H₅₁N₇O₇SSi₂
Molecular Weight:823.217
Hs Code.:

Synonyms:2',3'-di-O-(tert-butyldimethylsilyl)-5'-O-[N-(L-phenylalanyl)-sulfamoyl]adenosine triethylamine salt

Suppliers and Price of 2',3'-di-O-(tert-butyldimethylsilyl)-5'-O-[N-(L-phenylalanyl)-sulfamoyl]adenosine triethylamine salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2',3'-di-O-(tert-butyldimethylsilyl)-5'-O-[N-(L-phenylalanyl)-sulfamoyl]adenosine triethylamine salt

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2',3'-di-O-(tert-butyldimethylsilyl)-5'-O-[N-(L-phenylalanyl)-sulfamoyl]adenosine triethylamine salt

There total 1 articles about 2',3'-di-O-(tert-butyldimethylsilyl)-5'-O-[N-(L-phenylalanyl)-sulfamoyl]adenosine triethylamine salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1122489-87-5
2',3'-di-O-(tert-butyldimethylsilyl)-5'-O-[N-(N-Boc-L-phenylalanyl)-sulfamoyl]adenosine triethylamine salt

: 121-44-8
triethylamine

: 1122489-91-1
2',3'-di-O-(tert-butyldimethylsilyl)-5'-O-[N-(L-phenylalanyl)-sulfamoyl]adenosine triethylamine salt

Guidance literature:: 2',3'-di-O-(tert-butyldimethylsilyl)-5'-O-[N-(N-Boc-L-phenylalanyl)-sulfamoyl]adenosine triethylamine salt; With trifluoroacetic acid; In water; at 20 ℃; for 2h; Inert atmosphere;

triethylamine; In ethanol;
DOI:10.1016/j.bmc.2008.11.054

Reference yield: 96.0%

: 1122489-91-1
2',3'-di-O-(tert-butyldimethylsilyl)-5'-O-[N-(L-phenylalanyl)-sulfamoyl]adenosine triethylamine salt

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 1122490-02-1
2',3'-di-O-(tert-butyldimethylsilyl)-5'-O-[N-[N-(N-Boc-L-phenylalanyl)-L-phenylalanyl]-sulfamoyl]adenosine triethylamine salt

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1016/j.bmc.2008.11.054

Reference yield:

: 1122489-91-1
2',3'-di-O-(tert-butyldimethylsilyl)-5'-O-[N-(L-phenylalanyl)-sulfamoyl]adenosine triethylamine salt

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 1122490-04-3
5'-O-{[N-(N-L-phenylalanyl)-L-phenylalanyl]sulfamoyl}adenosine

Guidance literature:: Multi-step reaction with 2 steps

1.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere

2.1: trifluoroacetic acid / water / 2 h / 20 °C / Inert atmosphere

2.3: 20 °C / Inert atmosphere

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; In water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2008.11.054