2-phenyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyrano)-<2,1-d>-2-oxazoline

Base Information

• Chemical Name: 2-phenyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyrano)-<2,1-d>-2-oxazoline
• CAS No.: 10380-87-7
• Molecular Formula: C₁₉H₂₁NO₈
• Molecular Weight: 391.378
• Mol file: 10380-87-7.mol

Synonyms:2-phenyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyrano)-<2,1-d>-2-oxazoline

Chemical Property of 2-phenyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyrano)-<2,1-d>-2-oxazoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-phenyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyrano)-<2,1-d>-2-oxazoline

There total 7 articles about 2-phenyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyrano)-<2,1-d>-2-oxazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2,4,6-tetra-O-acetyl-2-benzamido-2-deoxy-β-D-glucopyranose (10385-49-6,14086-92-1) → 2-phenyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyrano)-<2,1-d>-2-oxazoline (10380-87-7)

Guidance literature:

With calcium sulfate; iron(III) chloride; In dichloromethane; Ambient temperature;

DOI:10.1016/0008-6215(85)85205-8

Reference yield:

benzoyl chloride (98-88-4) → 2-phenyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyrano)-<2,1-d>-2-oxazoline (10380-87-7)

Guidance literature:

Multi-step reaction with 2 steps

2: FeCl₃, CaSO₄ / CH₂Cl₂ / Ambient temperature

With calcium sulfate; iron(III) chloride; In dichloromethane;

DOI:10.1016/0008-6215(85)85205-8

Reference yield:

tetra-acetyl glucosamine (17460-45-6,23707-23-5,23739-93-7,23743-51-3,26108-75-8,59042-16-9,124516-07-0,124580-56-9) → 2-phenyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyrano)-<2,1-d>-2-oxazoline (10380-87-7)

Guidance literature:

Multi-step reaction with 2 steps

2: FeCl₃, CaSO₄ / CH₂Cl₂ / Ambient temperature

With calcium sulfate; iron(III) chloride; In dichloromethane;

DOI:10.1016/0008-6215(85)85205-8

upstream raw materials:

(3aR)-6t,7c-diacetoxy-5c-acetoxymethyl-2-phenyl-(3ar,7ac)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]oxazole; hydrobromide

1,2,4,6-tetra-O-acetyl-2-benzamido-2-deoxy-β-D-glucopyranose

benzoyl chloride

tetra-acetyl glucosamine

Downstream raw materials:

1,2:3,4-di-O-isopropylidene-6-O-(3,4,6-tri-O-acetyl-2-benzamido-2-deoxy-β-D-glucopyranosyl)-α-D-galactopyranose

ethyl-(tri-O-acetyl-2-benzoylamino-2-deoxy-β-D-glucopyranoside)

methyl-(tri-O-acetyl-2-benzoylamino-2-deoxy-β-D-glucopyranoside)

1,2,4,6-tetra-O-acetyl-2-benzamido-2-deoxy-β-D-glucopyranose