Thiazolo(3,2-a)benzimidazol-3(2H)-one, 2-((4-hydroxy-3-methoxyphenyl)methylene)-

Base Information

Chemical Name:Thiazolo(3,2-a)benzimidazol-3(2H)-one, 2-((4-hydroxy-3-methoxyphenyl)methylene)-
CAS No.:88498-93-5
Molecular Formula:C₁₇H₁₂N₂O₃S
Molecular Weight:324.36
Hs Code.:
Mol file:88498-93-5.mol

Synonyms:BRN 0302889;Thiazolo(3,2-a)benzimidazol-3(2H)-one, 2-((4-hydroxy-3-methoxyphenyl)methylene)-;4-27-00-07889 (Beilstein Handbook Reference);HMS1608P13;STK043664;AKOS000274080;SR-01000404864;SR-01000404864-1;Z44307729;(2E)-2-(4-hydroxy-3-methoxybenzylidene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one;2-[(E)-1-(4-HYDROXY-3-METHOXYPHENYL)METHYLIDENE][1,3]THIAZOLO[3,2-A][1,3]BENZIMIDAZOL-3(2H)-ONE

Suppliers and Price of Thiazolo(3,2-a)benzimidazol-3(2H)-one, 2-((4-hydroxy-3-methoxyphenyl)methylene)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Thiazolo(3,2-a)benzimidazol-3(2H)-one, 2-((4-hydroxy-3-methoxyphenyl)methylene)-

Chemical Property:

PSA：87.10000
LogP:2.78180
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:324.05686342
Heavy Atom Count:23
Complexity:512

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)C=C2C(=O)N3C4=CC=CC=C4N=C3S2)O
Isomeric SMILES:COC1=C(C=CC(=C1)/C=C/2\C(=O)N3C4=CC=CC=C4N=C3S2)O

Technology Process of Thiazolo(3,2-a)benzimidazol-3(2H)-one, 2-((4-hydroxy-3-methoxyphenyl)methylene)-

There total 3 articles about Thiazolo(3,2-a)benzimidazol-3(2H)-one, 2-((4-hydroxy-3-methoxyphenyl)methylene)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 3042-01-1
thiazolo[3,2-a]benzimidazol-3(2H)-one

: 121-33-5,8014-42-4
vanillin

: 88498-93-5
2-(p-hydroxy-m-methoxybenzylidene)thiazolo<3,2-a>benzimidazol-3(2H)-one

Guidance literature:: With sodium acetate; In ethanol; for 8h; Heating;

Reference yield:

: 3042-00-0
2-(1H-benzimidazol-2-ylthio)acetic acid

: 88498-93-5
2-(p-hydroxy-m-methoxybenzylidene)thiazolo<3,2-a>benzimidazol-3(2H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / Ac₂O, Py

2: 40 percent / NaOAc / ethanol / 8 h / Heating

With pyridine; sodium acetate; acetic anhydride; In ethanol;

Reference yield:

: 134469-07-1
Benzimidazol-2-thiol

: 88498-93-5
2-(p-hydroxy-m-methoxybenzylidene)thiazolo<3,2-a>benzimidazol-3(2H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: 65 percent / NaOH / H₂O / Heating

2: 70 percent / Ac₂O, Py

3: 40 percent / NaOAc / ethanol / 8 h / Heating

With pyridine; sodium hydroxide; sodium acetate; acetic anhydride; In ethanol; water;