2-Bromo-6-(2-(p-tolyl)-1,3-dioxolan-2-yl)pyridine

Base Information

Chemical Name:2-Bromo-6-(2-(p-tolyl)-1,3-dioxolan-2-yl)pyridine
CAS No.:87848-96-2
Molecular Formula:C15H14BrNO2
Molecular Weight:320.186
Hs Code.:2932999099
European Community (EC) Number:289-351-0
UNII:8PZ68KVY2P
DSSTox Substance ID:DTXSID00236665
Nikkaji Number:J334.020A
Wikidata:Q83118658
Mol file:87848-96-2.mol

Synonyms:87848-96-2;EINECS 289-351-0;2-Bromo-6-(2-(p-tolyl)-1,3-dioxolan-2-yl)pyridine;2-BROMO-6-[2-(P-TOLYL)-1,3-DIOXOLAN-2-YL]PYRIDINE;2-BROMO-6-[2-(4-METHYLPHENYL)-1,3-DIOXOLAN-2-YL]PYRIDINE;8PZ68KVY2P;SCHEMBL9827554;DTXSID00236665;Pyridine, 2-bromo-6-[2-(4-methylphenyl)-1,3-dioxolan-2-yl]-

Suppliers and Price of 2-Bromo-6-(2-(p-tolyl)-1,3-dioxolan-2-yl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-Bromo-6-(2-(p-tolyl)-1,3-dioxolan-2-yl)pyridine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:426.887°C at 760 mmHg
Flash Point:211.974°C
PSA：31.35000
Density:1.434g/cm³
LogP:3.40040
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:319.02079
Heavy Atom Count:19
Complexity:299

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2(OCCO2)C3=NC(=CC=C3)Br

Technology Process of 2-Bromo-6-(2-(p-tolyl)-1,3-dioxolan-2-yl)pyridine

There total 5 articles about 2-Bromo-6-(2-(p-tolyl)-1,3-dioxolan-2-yl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 87848-95-1
2-bromo-6-(4-toluoyl)pyridine

: 87848-96-2
2-(6-bromo-2-pyridyl)-2-(4-tolyl)-1,3-dioxolan

Guidance literature:: With sodium carbonate; toluene-4-sulfonic acid; In ethylene glycol; benzene;

Reference yield:

: 104-15-4
toluene-4-sulfonic acid

: 87848-95-1
2-bromo-6-(4-toluoyl)pyridine

: 87848-96-2
2-(6-bromo-2-pyridyl)-2-(4-tolyl)-1,3-dioxolan

Guidance literature:: With sodium carbonate; In ethylene glycol; benzene;

Reference yield:

: 626-05-1
2,6-Dibromopyridine

: 87848-96-2
2-(6-bromo-2-pyridyl)-2-(4-tolyl)-1,3-dioxolan

Guidance literature:: Multi-step reaction with 2 steps

1: 12.2 g / BuLi / hexane; diethyl ether / 3 h / -50 °C

2: 24.3 g / p-toluenesulfonic acid / toluene / 6 h / Heating

With n-butyllithium; toluene-4-sulfonic acid; In diethyl ether; hexane; toluene;
DOI:10.1002/jps.2600731003