4-(4-amino-5-bromo-6-chloropyrimidin-2-yloxy)-3,5-dimethylbenzonitrile

Base Information

• Chemical Name: 4-(4-amino-5-bromo-6-chloropyrimidin-2-yloxy)-3,5-dimethylbenzonitrile
• CAS No.: 1415796-12-1
• Molecular Formula: C₁₃H₁₀BrClN₄O
• Molecular Weight: 353.606
• Mol file: 1415796-12-1.mol

Synonyms:4-(4-amino-5-bromo-6-chloropyrimidin-2-yloxy)-3,5-dimethylbenzonitrile

Chemical Property of 4-(4-amino-5-bromo-6-chloropyrimidin-2-yloxy)-3,5-dimethylbenzonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(4-amino-5-bromo-6-chloropyrimidin-2-yloxy)-3,5-dimethylbenzonitrile

There total 1 articles about 4-(4-amino-5-bromo-6-chloropyrimidin-2-yloxy)-3,5-dimethylbenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-bromo-2,6-dichloropyrimidin-4-amine (101012-11-7) + 3,5-dimethyl-4-hydroxybenzonitrile (4198-90-7) → 4-(4-amino-5-bromo-6-chloropyrimidin-2-yloxy)-3,5-dimethylbenzonitrile (1415796-12-1) + 4-(6-amino-5-bromo-2-chloropyrimidin-4-yloxy)-3,5-dimethylbenzonitrile (1415796-11-0) + 4,4'-(6-amino-5-bromopyrimidine-2,4-diyl)bis(oxy)-bis(3,5-dimethylbenzonitrile) (1415796-13-2)

Guidance literature:

5-bromo-2,6-dichloropyrimidin-4-amine; With sodium hydride; In ISOPROPYLAMIDE; mineral oil; at 0 - 5 ℃; for 0.333333h; Inert atmosphere;

3,5-dimethyl-4-hydroxybenzonitrile; In ISOPROPYLAMIDE; mineral oil; at 10 - 80 ℃; for 19.5h;

upstream raw materials:

5-bromo-2,6-dichloropyrimidin-4-amine

3,5-dimethyl-4-hydroxybenzonitrile