Benzoic acid (E)-(S)-6-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-hex-2-enyl ester

Base Information

Chemical Name:Benzoic acid (E)-(S)-6-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-hex-2-enyl ester
CAS No.:334706-33-1
Molecular Formula:C₂₇H₃₈O₅Si
Molecular Weight:470.681
Hs Code.:

Synonyms:Benzoic acid (E)-(S)-6-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-hex-2-enyl ester

Suppliers and Price of Benzoic acid (E)-(S)-6-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-hex-2-enyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Benzoic acid (E)-(S)-6-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-hex-2-enyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Benzoic acid (E)-(S)-6-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-hex-2-enyl ester

There total 6 articles about Benzoic acid (E)-(S)-6-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-hex-2-enyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 98-88-4
benzoyl chloride

: 334706-39-7
(E)-(S)-6-(tert-Butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-hex-2-en-1-ol

: 334706-33-1
Benzoic acid (E)-(S)-6-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-hex-2-enyl ester

Guidance literature:: With pyridine; dmap; In dichloromethane; at 20 ℃; for 16h;
DOI:10.1016/S0040-4039(00)02115-8

Reference yield: 65.0%

: 65-85-0,8013-63-6
benzoic acid

: 334972-54-2
(S)-tert-butyl((2-((4-methoxybenzyl)oxy)hex-5-en-1-yl)oxy)dimethylsilane

: 334706-33-1
Benzoic acid (E)-(S)-6-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-hex-2-enyl ester

Guidance literature:: With tetrakis(acetonitrile)palladium(II) bis(tetrafluoroborate); dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine; 2-phenyl-1,4-benzoquinone; In dichloromethane; at 41 ℃; for 72h; optical yield given as %de; Molecular sieve;
DOI:10.1021/ja104826g

Reference yield:

: 89238-99-3
O-(4-methoxybenzyl)-trichloroacetimidate

: 334706-33-1
Benzoic acid (E)-(S)-6-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-hex-2-enyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 76 percent / BF₃*OEt₂ / CH₂Cl₂ / 1 h / -78 °C

2: 99 percent / DIBAL / toluene / 0.08 h / -78 °C

3: 90 percent / benzene / 1 h / Heating

4: 99 percent / Et₃N; DMAP / CH₂Cl₂ / 2 h

5: 97 percent / DIBAL / toluene / 2 h / -78 °C

6: 82 percent / pyridine; DMAP / CH₂Cl₂ / 16 h / 20 °C

With pyridine; dmap; boron trifluoride diethyl etherate; diisobutylaluminium hydride; triethylamine; In dichloromethane; toluene; benzene;
DOI:10.1016/S0040-4039(00)02115-8